Background@#
Postoperative nausea and vomiting (
PONV ) commonly occurs after
spinal anesthesia ; however, its
incidence rate and predictors have been scarcely studied. Therefore, we aimed to investigate its
incidence rate and potential predictors. @*
Methods @#The
electronic medical records of 6,610 consecutive
patients undergoing
orthopedic surgery under
spinal anesthesia were reviewed between January 2016 and December 2020. The primary outcome was
PONV incidence within 24 h after
spinal anesthesia . Along with its
incidence rate , we investigated its predictors using multivariable
logistic regression analysis . @*Results@#Among the 5,691
patients included in the
analysis , 1,298 (22.8%) experienced
PONV within 24 h after
spinal anesthesia .
Female sex (
odds ratio [OR] 3.23, 95% CI [2.72, 3.83], P < 0.001),
nonsmoker (OR 2.12, 95% CI [1.46, 3.07], P < 0.001),
history of
PONV (OR 1.52, 95% CI [1.26, 1.82], P < 0.001), prophylactic
5-hydroxytryptamine receptor antagonist use (OR 0.35, 95% CI [0.24, 0.50], P < 0.001), prophylactic
steroid use (OR 0.53, 95% CI [0.44, 0.62], P < 0.001), baseline
heart rate ≥ 60 beats/min (OR 1.38, 95% CI [1.10, 1.72], P = 0.005), and postoperative
opioid use (OR 2.57, 95% CI [1.80, 3.67], P < 0.001), were significant predictors of the primary outcome. @*Conclusions@#Our study showed the common
incidence of
PONV after
spinal anesthesia and its significant predictors. A better
understanding of its predictors may provide important information for its management.