Objective@#To investigate the
prevalence of
depression and
anxiety among
transgender populations and the correlation with defense mechanism, so as to provide the evidence for improving
mental health among
transgender populations. @*
Methods@#
Transgender populations that visited Psychosexual
Outpatient Department of
Beijing Huilongguan
Hospital for the first
time from December 2020 to December 2021 were enrolled. Participants' demographics,
depression,
anxiety and type of
defense mechanisms were collected using
self-designed
questionnaires,
Self-rating
Depression Scale,
Self-rating
Anxiety Scale and Defense Style
Questionnaire (DSQ). Factors affecting
depression and
anxiety were identified using a multivariable
logistic regression model. @*Results@#Totally 126
transgender individuals were enrolled, including 95
men (75.40%) with a mean age of (21.53±4.55) years and 31
women (24.60%) with a mean age of (23.58±5.55) years. The
prevalence of
depression was 46.83% among participants, including 44.07% of participants with mild
depression, 30.51% with moderate
depression and 25.42% with severe
depression, and the
prevalence of
anxiety was 26.19% among participants, including 60.61% of participants with mild
anxiety, 21.21% with moderate
anxiety and 18.18% with severe
anxiety. The
detection of
depression was 54.74% among
men and 22.58% among
women (P<0.05), and the
detection of both
depression (62.79% vs. 38.55%, P<0.05) and
anxiety (41.86% vs. 18.07%, P<0.05) was significantly higher among
transgender populations with
self-injury or
suicide behaviors than among those without. Multivariable
logistic regression analysis showed that immature
defense mechanisms increased the
risk of
depression (OR=1.034, 95%CI 1.018-1.051) and
anxiety (OR=1.031, 95%CI 1.014-1.049) among
transgender populations, while mature
defense mechanisms reduced the
risk of
depression (OR=0.887, 95%CI 0.832-0.946) and
anxiety (OR=0.878, 95%CI 0.821-0.938) among
transgender populations.@*Conclusions@#The
prevalence of
depression and
anxiety was 46.83% and 26.19% among
transgender populations included in this study. Mature
defense mechanisms are beneficial to reduce the
risk of
depression and
anxiety among
transgender populations. Key words:
transgender population depression anxiety defense mechanism