Evaluation of Renal Impairment in Patients with Diabetic Kidney Disease by Integrated Chinese and Western Medicine / 中国结合医学杂志
Yi-Lun QU; Zhe-Yi DONG; Hai-Mei CHENG; Qian LIU; Qian WANG; Hong-Tao YANG; Yong-Hui MAO; Ji-Jun LI; Hong-Fang LIU; Yan-Qiu GENG; Wen HUANG; Wen-Hu LIU; Hui-di XIE; Fei PENG; Shuang LI; Shuang-Shuang JIANG; Wei-Zhen LI; Shu-Wei DUAN; Zhe FENG; Wei-Guang ZHANG; Yu-Ning LIU; Jin-Zhou TIAN; Xiang-Mei CHEN.
Chinese journal of integrative medicine
; (12): 308-315, 2023.
Artículo
en Inglés
| WPRIM | ID: wpr-982278
OBJECTIVE@#To investigate the factors related to renal impairment in patients with diabetic kidney disease (DKD) from the perspective of integrated Chinese and Western medicine.@*METHODS@#Totally 492 patients with DKD in 8 Chinese hospitals from October 2017 to July 2019 were included. According to Kidney Disease Improving Global Outcomes (KDIGO) staging guidelines, patients were divided into a chronic kidney disease (CKD) 1-3 group and a CKD 4-5 group. Clinical data were collected, and logistic regression was used to analyze the factors related to different CKD stages in DKD patients.@*RESULTS@#Demographically, male was a factor related to increased CKD staging in patients with DKD (OR=3.100, P=0.002). In clinical characteristics, course of diabetes >60 months (OR=3.562, P=0.010), anemia (OR=4.176, P<0.001), hyperuricemia (OR=3.352, P<0.001), massive albuminuria (OR=4.058, P=0.002), atherosclerosis (OR=2.153, P=0.007) and blood deficiency syndrome (OR=1.945, P=0.020) were factors related to increased CKD staging in patients with DKD.@*CONCLUSIONS@#Male, course of diabetes >60 months, anemia, hyperuricemia, massive proteinuria, atherosclerosis, and blood deficiency syndrome might indicate more severe degree of renal function damage in patients with DKD. (Registration No. NCT03865914).
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