OBJECTIVE@#To analyze the clinical characteristics of
patients with
emergency in-
hospital cardiac arrest (IHCA) in Kashgar, Xinjiang Uygur Autonomous Region and the factors affecting the success rate of
cardiopulmonary resuscitation .@*
METHODS @#Retrospectively selected
patients who had
cardiac arrest and
cardiopulmonary resuscitation in the
emergency department of the People's
Hospital of 6 counties and cities in Kashgar area from January 2019 to January 2022. The clinical data of all
patients were collected, including
gender , age, major underlying
diseases , the beginning and duration of
resuscitation , the number of
electric defibrillation acute physiology and chronic health evaluation II (
APACHE II ). According to whether the
resuscitation was successful, all
patients were divided into successful
resuscitation group and failed
resuscitation group. The clinical characteristics of the two groups were compared. Then, the influencing factors of the success rate of
cardiopulmonary resuscitation in IHCA
patients were analyzed by binary
Logistic regression .@*RESULTS@#A total of 1 376
patients were enrolled, including 1 117 cases of failed
resuscitation and 259 cases of successful
resuscitation . The success rate of
resuscitation was 18.82%. Compared with the
resuscitation failure group, the
patients in the successful
resuscitation group were younger (age 49.10±20.99 vs. 58.44±18.32), the
resuscitation start
time was earlier [
resuscitation start
time ≤ 5 minutes 76.45% (198/259) vs. 66.61% (744/1 117)], the proportion of cardiovascular and
cerebrovascular diseases was lower [
cardiovascular disease 49.42% (128/259) vs. 58.19% (650/1 117),
cerebrovascular disease 17.37% (45/259) vs. 21.58% (241/1 117)], the number of
electric defibrillation was lower [times 0 (0, 2) vs. 1 (0, 1)], the proportion of
endotracheal intubation was more [80.31% (208/259) vs. 55.60% (621/1 117)],
APACHE II score was lower (13.75±8.03 vs. 17.90±4.63), and the difference was statistically significant (all P < 0.01). Binary
Logistic regression analysis showed that age, start
time of
resuscitation ,
ventilation mode and
APACHE II score were
protective factors affecting the success rate of
cardiopulmonary resuscitation in
patients with
emergency IHCA [age
odds ratio (OR) = 0.982, 95%
confidence interval (95%CI) was 0.973-0.991, P < 0.001;
resuscitation start
time ≤ 5 minutes OR = 0.629, 95%CI was 0.409-0.966, P = 0.034; tracheal
intubation assisted
ventilation OR = 0.243, 95%CI was 0.149-0.397, P < 0.001; low
APACHE II score OR = 0.871, 95%CI was 0.836-0.907, P < 0.001], while underlying
diseases (
cardiovascular diseases ) are a
risk factor affecting the success rate of
cardiopulmonary resuscitation (OR = 1.190, 95%CI was 1.015-1.395, P = 0.036).@*CONCLUSIONS@#Age,
resuscitation start
time ,
ventilation mode,
APACHE II score and major underlying
diseases (
cardiovascular diseases ) have a greater impact on the success rate of
resuscitation in IHCA
patients . The above factors are conducive to improving or formulating more effective rescue
strategies for IHCA
patients , so as to achieve the purpose of improving the success rate of clinical
treatment .