Fundus oculi proliferative
diseases, such as
choroidal neovascularization,
diabetic retinopathy, and
proliferative vitreoretinopathy, are characterized by
cell proliferation and neovascularization.It can
lead to damage to the ocular structure and
visual acuity.
Circular RNA (
CircRNA) is a non-
coding endogenous
RNA, which has been confirmed to be involved in the pathophysiological process of many ophthalmic
diseases by recent studies.Thus,
circRNA may become a promising target of
fundus oculi proliferative
diseases.This
review concluded the physiological function of
circRNA and its
role in the physiological and pathological process of
diabetic retinopathy,
proliferative vitreoretinopathy and
glaucoma-related
glia proliferation.