ABSTRACT
La aspergilosis pulmonar necrotizante crónica es una rara enfermedad que tiende a afectar a personas con enfermedad pulmonar subyacente o inmuno comprometidos en grado leve. Es una complicación excepcional de la silicosis y su diagnóstico precisa un alto índice de sospecha pues simula otras enfermedades como tuberculosis y neoplasia, complicaciones más frecuentes en estos pacientes. Presentamos tres casos con larga historia de exposición a sílice y diagnóstico de fibrosis masiva progresiva que presentaron aspergilosis pulmonar. Revisamos sus características clínicas, radiológicas y tratamiento(AU)
Chronic necrotizing pulmonary aspergillosis is un uncommon disease which is found in people with underlying lung disease or in mildly immune compromised patients. It is an exceptional complication in silicosis and its diagnosis is difficult because it simulates other diseases like tuberculosis and cancer which are more common in such patients. We report on three cases with a long history of silica dust exposure with pulmonary aspergillosis complicating progressive massive fibrosis(PMF). We review their clinical, radiological and treatment features(AU)
Subject(s)
Humans , Male , Adult , Aspergillosis/diagnosis , Silicosis/complications , Aspergillus flavus/isolation & purification , Aspergillus fumigatus/isolation & purification , Itraconazole/therapeutic use , Antifungal Agents/therapeutic useABSTRACT
We present the case of an asymptomatic male in whom bilateral hilar and right paratracheal lymph node enlargement was a casual finding. An esophagogram was performed to evaluate possible mediastinal nodes and an esophagobronchial fistula was discovered. In view of the coexistence of lymph node enlargement and esophagobronchial fistula, the case was presumed to be tuberculosis, as was confirmed by sputum culture positive for Mycobacterium tuberculosis. After tuberculostatic treatment, the course was favorable. Closure of the fistula was confirmed in a later follow-up.
