Short-term outcomes of pregnant women with convalescent COVID-19 and factors associated with false-negative polymerase chain reaction test: A prospective cohort study.

AIM: To evaluate the clinical factors associated with false-negative RT-PCR results and to report the outcome of a cohort of pregnant women with COVID-19. METHODS: This cohort study was conducted in a tertiary referral pandemic hospital and included 56 pregnant women. A study including pregnant women with either a laboratory or clinical diagnosis for COVID-19 were included in the study. The primary outcome was clinical factors associated with false-negative RT-PCR results defined as a positive immunoglobulin M assessed by rapid testing in clinically diagnosed patients. Clinical outcomes of laboratory diagnosed patients were also reported. RESULTS: In total, 56 women with either RT-PCR or clinical COVID-19 diagnosis were included in the study. Forty-three women either had RT-PCR positivity or IgM positivity. The clinical outcome of these pregnancies was as follows: mean maternal age 27.7, immunoglobulin M positive patients 76.7%, RT-PCR positive patients 55.8%, maternal comorbidities 11.5%, complications in patients below 20 weeks 34.8%, complications in patients above 20 weeks 65.1%, elevated CRP 83.7%, lymphopenia 30.2%, time from hospital admission to final follow-up days 37 and stillbirth 8.3%. The proportion of women who tested positive for SARS-CoV-2 immunoglobulin M was 100% in the RT-PCR positive group and 56.5% in the clinical diagnosis group (P = .002). The symptom onset to RT-PCR testing interval longer than a week (risk ratio: 2.72, 95% CI: 1.14-5.40, P = .003) and presence of dyspnoea (risk ratio: 0.38, 95% CI: 0.14-0.89, P = .035) were associated with false-negative RT-PCR tests. The area under the curve of these parameters predicting false-negative RT-PCR was 0.73 (95% CI: 0.57-0.89). CONCLUSIONS: Symptomatic women with a negative RT-PCR should not be dismissed as potential COVID-19 patients, especially in the presence of prolonged symptom onset-test interval and in women without dyspnoea.

Depression and anxiety levels in mothers of children with epistaxis: A controlled study / Niveles de depresión y ansiedad en madres de niños con epistaxis: un estudio controlado

Introduction: Pediatric epistaxis is very common. A child's illness can lead to depression and anxiety in the parents. The association between pediatric epistaxis and mothers’ anxiety has not been well documented. Objective: The present study is aimed at measuring depression and anxiety levels in mothers of children with mild, recurrent epistaxis. Methods: This prospective, clinical, questionnaire-based study examined 43 mothers of children with recurrent epistaxis and 42 mothers of healthy children. The depression and anxiety levels of the mothers in both the groups were assessed with the Beck Depression Inventory (BDI), the state-trait anxiety inventory-state (STAI-S), and the state-trait anxiety inventory-trait (STAI-T). Results: No statistically-significant differences were found between the two groups of mothers in terms of educational level, employment, age, or economic status. The mean STAI-S scores were higher in the mothers of children with epistaxis (p = .010). However, no statistically-significant differences were found between the two groups for the BDI and STAI-T scores. Conclusions: The results of this comparative study suggest that mild, recurrent epistaxis in children can significantly increase their mothers' state anxiety levels, but epistaxis has no significant effect on either depression or trait anxiety

Introducción: La epistaxis pediátrica es muy común. La enfermedad de un niño puede provocar depresión y ansiedad en los padres. La asociación entre la epistaxis pediátrica y la ansiedad de las madres no ha sido bien documentada. Objetivo: El presente estudio tuvo como objetivo medir los niveles de depresión y ansiedad en madres de niños con epistaxis recurrente leve. Métodos: Este estudio prospectivo, clínico y basado en cuestionarios, examinó a 43 madres de niños con epistaxis recurrente y 42 madres de niños sanos. Los niveles de depresión y ansiedad de las madres en ambos grupos se evaluaron con el Inventario de Depresión de Beck (BDI), el estado de inventario de ansiedad con rasgo de estado (STAI-S) y el rasgo de inventario de ansiedad con rasgo de estado (STAI-T). Resultados: No se encontraron diferencias estadísticamente significativas entre los 2 grupos de madres en términos de nivel educativo, empleo, edad o estado económico. Las puntuaciones promedio de STAI-S fueron más altas en las madres de niños con epistaxis (p = 0,010). Sin embargo, no se encontraron diferencias estadísticamente significativas entre los 2 grupos para las puntuaciones BDI y STAI-T. Conclusiones: Los resultados de este estudio comparativo sugieren que la epistaxis leve y recurrente en los niños puede aumentar significativamente los niveles de ansiedad del estado de sus madres, pero la epistaxis no tiene un efecto significativo sobre la depresión o la ansiedad

Depression and anxiety levels in mothers of children with epistaxis: A controlled study.

INTRODUCTION: Pediatric epistaxis is very common. A child's illness can lead to depression and anxiety in the parents. The association between pediatric epistaxis and mothers' anxiety has not been well documented. OBJECTIVE: The present study is aimed at measuring depression and anxiety levels in mothers of children with mild, recurrent epistaxis. METHODS: This prospective, clinical, questionnaire-based study examined 43 mothers of children with recurrent epistaxis and 42 mothers of healthy children. The depression and anxiety levels of the mothers in both the groups were assessed with the Beck Depression Inventory (BDI), the state-trait anxiety inventory-state (STAI-S), and the state-trait anxiety inventory-trait (STAI-T). RESULTS: No statistically-significant differences were found between the two groups of mothers in terms of educational level, employment, age, or economic status. The mean STAI-S scores were higher in the mothers of children with epistaxis (p=.010). However, no statistically-significant differences were found between the two groups for the BDI and STAI-T scores. CONCLUSIONS: The results of this comparative study suggest that mild, recurrent epistaxis in children can significantly increase their mothers' state anxiety levels, but epistaxis has no significant effect on either depression or trait anxiety.

Reattachment of a partially amputated ear without microsurgery.

Traumatic ear amputations are relatively rare. Whenever possible, ear re-implantation should be attempted; however the choice of the surgical procedure must be judicious. In the current report, a case of complete non-microsurgical salvage of a partially amputated ear treated by the pocket technique described by Mladick was presented. The surgical technique is described in detail by serial photographs, along with the postoperative management and outcome of the patients. The revascularisation of the severed part was successful. Morphological result was very good when the ear was freed from the pocket. We recommend the Mladick's procedure for reimplantation of fragments less than 1/2 of the auricle with favourable tissue condition.

Boomerang-Shaped Chondro-Perichondral Graft Versus Temporalis Muscle Fascia Graft: Which One is to be Trusted?

The aim of this study was to compare anatomical and audiological results of boomerang-shaped chondroperichondrial graft (BSCPG) with temporal muscle fascia in type 1 tympanoplasties. Sixty-eight patients in BSCPG group and 54 patients in fascia group were evaluated. Otomicroscopic examination was done periodically till 24 months as for graft perforation, lateralization and retraction and mean air conduction threshold and airbone gap values were measured. At long term controls, in BSCPG group, rates of neomembrane, perforation, retraction and lateralization were 91.17 % (n = 62), 8.82 % (n = 6), 4.41 % (n = 3) and 0 % (n = 0), respectively. In fascia group, the corresponding rates were 79.62 % (n = 43), 20.37 % (n = 11), 12.96 % (n = 7) and 3.7 % (n = 2), respectively. In both groups, mean postoperative PTA and ABG values were significantly better while postoperative same values were significantly different between groups (p = 0.044 and 0.032, respectively). Compared to fascia, BSCPG is an ideal grafting technique in the repair of tympanic membrane perforations.