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1.
Neurol India ; 72(1): 142-144, 2024 Jan 01.
Article in English | MEDLINE | ID: mdl-38443016

ABSTRACT

ABSTRACT: Dural venous sinus cysts are very infrequent lesions, generally asymptomatic and incidental. These cystic lesions may include venous structures continuing with superficial cortical veins. A 23-year-old male patient presented with a severe headache. Cranial computed tomography and contrast-enhanced magnetic resonance imaging demonstrated a well-defined, central curvilinear enhanced lesion, located in the superior sagittal sinus which was compatible with the intraluminal dural venous cyst. The patient was included imaging follow-up for possible growth of this cystic lesion. Dural venous sinus cysts are asymptomatic lesions by far. However, these incidental lesions should be followed up just in case the progression-occlusion of the dural sinus. Possible venous components that may have connections with cortical veins should be considered in terms of surgery.


Subject(s)
Cysts , Superior Sagittal Sinus , Humans , Male , Young Adult , Skull , Tomography, X-Ray Computed
3.
Photodiagnosis Photodyn Ther ; 41: 103247, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36539005

ABSTRACT

BACKGROUND: Flow-diverting stents are devices that are increasingly used in the treatment of intracranial aneurysms and expand the spectrum of endovascular treatment. The patency of side branches and perforators is a major concern about flow-diverting stent (FDS) treatment. METHODS: From 2011 to 2020, seventy-eight patients in whom the orifice of the ophthalmic artery was covered during FDS treatment were evaluated in this study. Bilateral retinal vascular parameters of study subjects were evaluated with OCT and OCTA. The FDS implanted-side eyes of the patients were defined as the procedure group, and the fellow eyes were considered as the control group. RESULTS: Twenty-seven patients who were treated with FDS covering the ostium of the ophthalmic artery and who could undergo full ophthalmologic examination were included in the study. There was no statistically significant difference found in terms of visual acuity, retinal vascular parameters, and choroidal thickness between the procedure group and the control group (p>0.05). However, in one case, recanalized retinal artery branch occlusion was detected on the side where the FDS was implanted. CONCLUSION: The orifice of the ophthalmic artery is often covered during FDS treatment for carotid-ophthalmic aneurysms; however, this treatment approach has no significant effect on ophthalmic vascular parameters.


Subject(s)
Ophthalmic Artery , Photochemotherapy , Humans , Ophthalmic Artery/diagnostic imaging , Treatment Outcome , Photochemotherapy/methods , Photosensitizing Agents , Stents/adverse effects
4.
Growth Horm IGF Res ; 68: 101521, 2023 02.
Article in English | MEDLINE | ID: mdl-36427362

ABSTRACT

OBJECTIVE: We investigated the coexistence of newly diagnosed acromegaly with primary empty sella (ES), which is considered to be a rare association, and the impact of ES on the laboratory, radiological and prognostic status of acromegaly. DESIGN: Acromegaly patients diagnosed and followed-up between 2012 and 2021 were included. Empty sella was defined as the pituitary gland and adenoma filling <50% of the sella turcica on preoperative T1 magnetic resonance imaging (MRI). RESULTS: 102 acromegalic patients (45 male, 57 female, 45.5 ± 12.8 (range: 20-70 years) were included and data of a median 3 years (range: 0.5-9 years) were presented. ES was detected in 19 (18.6%) patients and 4 had complete and 15 had partial ES. Although not significant, adenoma size and residual adenoma on MRI on postoperative 3rd month, and disease remission at last control were lower in acromegaly with ES than in acromegaly without ES, while the rate of female gender and remission on postoperative 3rd month were higher. While preoperative serum prolactin and nadir GH responses to OGTT were significantly lower in patients with ES, there was no difference in terms of other pituitary hormones among both groups. CONCLUSION: The present study revealed the coexistence of newly diagnosed acromegaly with primary ES at a rate of nearly 20% which is more frequent than expected and this association is not rare. The presence of ES was not associated with any preoperative/postoperative pituitary hormone levels and remission status, except lower preoperative prolactin and nadir GH responses to OGTT.


Subject(s)
Acromegaly , Adenoma , Empty Sella Syndrome , Pituitary Neoplasms , Humans , Male , Female , Acromegaly/complications , Acromegaly/diagnosis , Prolactin , Adenoma/complications , Adenoma/diagnosis , Adenoma/surgery , Growth Hormone , Magnetic Resonance Imaging , Empty Sella Syndrome/complications , Empty Sella Syndrome/diagnostic imaging , Pituitary Neoplasms/diagnosis , Pituitary Neoplasms/diagnostic imaging
6.
J Comput Assist Tomogr ; 46(2): 269-273, 2022.
Article in English | MEDLINE | ID: mdl-35081604

ABSTRACT

OBJECTIVE: This study aimed to evaluate the utility of computed tomography (CT) guidance in difficult lumbar puncture (LP) cases, which had a history of at least one unsuccessful blind attempt at LP (no imaging guidance), and to note potential advantages and disadvantages of the use of CT guidance. METHODS: In total, 32 CT-guided LP procedures performed between June 2019 and March 2021 were included. All LP indications were recorded. The procedures where the cerebrospinal fluid flow was provided by a single puncture were evaluated as "primary technical success." "Secondary technical success" corresponded with the procedures in which additional puncture was necessary for the cerebrospinal fluid flow. RESULTS: Intrathecal nusinersen injections due to spinal muscular atrophy constituted the largest procedure group of this study. Among 32 procedures, primary and secondary technical success rates were 78.12% and 28.57%, respectively. There were no major procedural complications. CONCLUSIONS: Computed tomography-guided LP is an effective interventional technique offering an alternative approach in the setting of difficult LP procedures.


Subject(s)
Muscular Atrophy, Spinal , Spinal Puncture , Humans , Injections, Spinal/methods , Muscular Atrophy, Spinal/drug therapy , Tomography, X-Ray Computed
7.
Eur Arch Otorhinolaryngol ; 279(2): 875-882, 2022 Feb.
Article in English | MEDLINE | ID: mdl-33988752

ABSTRACT

PURPOSE: To report the results of the endovascular treatment of acute-massive head and neck bleeding in a single center and underline the value of computerized tomography-angiography and endovascular treatment of this desperate patient group. METHODS: Forty-eight patients who suffered from acute-massive head and neck bleeding and in whom conservative treatment options had failed were included in the study. To localize the site of the bleeding, computerized tomography-angiography was obtained above the supra-aortic level. Depending on the type and site of bleeding, an urgent angiographic evaluation and appropriate endovascular treatment procedure were performed in the same session immediately. Complete control of all active bleeding was determined as "technical success" at the end of the procedure. RESULTS: The majority of the endovascular treatment indications were tumoral mass bleedings in this study. Eight patients, all of which had head and neck tumors as the cause of the bleeding underwent repeated interventional procedures due to acute re-bleeding. All patients left the angiography unit with technical success and dramatic clinical improvement. Two patients had procedure-related severe complications, such as contrast-induced nephropathy and acute cerebrovascular accident. One patient died due to massive re-bleeding during the follow-up period. CONCLUSION: Computerized tomography-angiography is a successful imaging method to reveal the location and cause of bleeding. Endovascular treatment of acute-massive head and neck bleeding is an effective and life-saver treatment option that can be used successfully with relatively low-risk potential.


Subject(s)
Embolization, Therapeutic , Endovascular Procedures , Computed Tomography Angiography , Head/diagnostic imaging , Hemorrhage/diagnostic imaging , Hemorrhage/etiology , Hemorrhage/therapy , Humans , Neck/diagnostic imaging , Retrospective Studies , Treatment Outcome
8.
Turk Neurosurg ; 31(4): 661-664, 2021.
Article in English | MEDLINE | ID: mdl-33978207

ABSTRACT

AIM: To present an alternative endovascular treatment option for the vein of Galen aneurysmal malformation by ethylene-vinyl alcohol copolymer embolization via a double-lumen balloon microcatheter. MATERIAL AND METHODS: A female patient was suspected with the vein of Galen aneurysmal malformation in the prenatal period and diagnosed choroidal type vein of Galen aneurysmal malformation. Once the patient was symptomatic with severe cardiac failure, an endovascular treatment decision was made. In the first step, a mixture of N-butyl cyanoacrylate-lipiodol was used for embolization. In the second session of the treatment, ethylene-vinyl alcohol copolymer was administered through a double-lumen balloon microcatheter. RESULTS: Complete cure of the aneurysmal malformation was obtained by no filling was observed in arterial feeders, collapsed appearance of the vein of Galen, and arterial-venous shunts at the end of the five-year follow-up period with magnetic resonance imaging and angiography. CONCLUSION: Ethylene-vinyl alcohol copolymer embolization via double-lumen balloon microcatheter provides an alternative and effective endovascular treatment option for the vein of Galen aneurysmal malformations using less contrast agent in less procedural time. Also, the possibility of spontaneous regression of residual aneurysmal malformations with small feeders should be considered.


Subject(s)
Balloon Occlusion/methods , Chemoembolization, Therapeutic/methods , Endovascular Procedures/methods , Polyvinyls/therapeutic use , Vein of Galen Malformations/therapy , Combined Modality Therapy , Contrast Media/therapeutic use , Female , Humans , Infant, Newborn , Intensive Care, Neonatal , Magnetic Resonance Imaging , Pregnancy , Prenatal Diagnosis , Treatment Outcome , Turkey , Vein of Galen Malformations/diagnosis
9.
Arch Med Sci ; 16(1): 58-65, 2020.
Article in English | MEDLINE | ID: mdl-32051706

ABSTRACT

INTRODUCTION: The aim of this study was to evaluate 3-dimensional (3D) ultrasonography (US) in determining the surface irregularity of carotid artery plaques. MATERIAL AND METHODS: This study included 50 patients (20 females and 30 males) aged between 56 and 82 years with plaques in the carotid artery which were detected during routine neck ultrasound. Simultaneously these cases were evaluated in terms of plaque echogenicities and surface characteristics with 2D and 3D US. RESULTS: 3D imaging was successfully performed in 45 of the 50 cases and the technical success rate was 90%. A single plaque was detected in 64.4% of the patients, with the remaining 35.6% having more than one plaque. The lengths of the plaques ranged from 2 to 12 mm (mean: 3.98 ±1.70 mm); the widths ranged from 1.8 to 3.2 mm (mean: 2.11 ±0.37 mm). No significant difference was found between 2D and 3D plaque echo-structures (observer 1, p = 0.317; observer 2, p = 0.276), but there were significant differences between 2D and 3D plaque surface irregularities (observer 1, p = 0.002; observer 2, p = 0.004). The inter-observer agreement on 2D and 3D plaque echo-structure and surface irregularity was very good (k coefficients were 0.89 and 0.83, respectively, for echo-structure, and 0.91 and 0.95, respectively, for surface irregularity). CONCLUSIONS: The present study shows that 3D US examination is a valuable non-invasive method for investigation of surface irregularity of carotid artery plaques.

10.
Turk Neurosurg ; 28(3): 405-409, 2018.
Article in English | MEDLINE | ID: mdl-28345124

ABSTRACT

AIM: To evaluate microcirculatory changes in neighboring parenchyma as a result of pressure due to chronic subdural hematoma (CSDH) in early and late periods after hematoma drainage. MATERIAL AND METHODS: The subject group consisted of 25 patients who underwent CSDH drainage. Brain diffusion and perfusion magnetic resonance images (MRIs) were obtained preoperatively, and at 48 hours (early period) and 2 months (late period) postoperatively. Measurements were performed on 1 cm2 regions of interest (ROI) in the neighboring parenchymal tissue. RESULTS: The early postoperative diffusion values showed improvement compared to the preoperative values. The late postoperative values showed improvement compared to the preoperative and early postoperative values. The early postoperative perfusion values showed slight decline compared to the preoperative values. However, the late postoperative values showed improvement compared to the preoperative and early postoperative values. CONCLUSION: The fact that there was an increase in diffusion values from early to late postoperative periods, compared with the preoperative period, indicates that the beneficial effects of surgery increase over time. Brain perfusion was found to be slightly decreased in early postoperative period. Following CSDH drainage, neurological deteriorations are observed in some patients in the early postoperative periods; a slight impairment in perfusion may account for this. However, during the late postoperative period, perfusion was seen to recover prominently.


Subject(s)
Brain/diagnostic imaging , Cerebrovascular Circulation/physiology , Hematoma, Subdural, Chronic/physiopathology , Hematoma, Subdural, Chronic/surgery , Adult , Aged , Brain/physiopathology , Drainage/methods , Female , Hematoma, Subdural, Chronic/diagnostic imaging , Humans , Magnetic Resonance Imaging , Male , Microcirculation , Middle Aged , Postoperative Period
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