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1.
Sci Rep ; 14(1): 15928, 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38987632

ABSTRACT

This study investigates a novel method to control hypersonic boundary layer transition using a combined local cooling and local metasurface treatment. The method's effectiveness was investigated on a 5-degree half-angle blunt wedge with a nose radius of 0.0254 mm at a freestream Mach number of 6.0 using direct numerical simulations and linear stability theory. We explored four cases: (i) adiabatic baseline case, (ii) locally cooled case, (iii) local metasurface case, and (iv) combined local cooling-local metasurface case. Results showed that the combined local cooling-local metasurface treatment significantly reduced both wall pressure disturbance amplitude and the density perturbation amplitude around the sonic line, indicating a potential for controlling hypersonic boundary layer transition. In the local cooling-local metasurface case, the disturbance amplitude at the end of the computational domain was 270 times lower than the baseline case. The study also examined the impact of Reynolds numbers, ranging from 25.59 million per meter to 32.80 million per meter. Unsteady simulations revealed that the Reynolds number had a negligible effect on the local cooling-local metasurface performance, indicating that the proposed method applies to a wide range of flight conditions.

2.
Photodiagnosis Photodyn Ther ; 43: 103681, 2023 Sep.
Article in English | MEDLINE | ID: mdl-37390853

ABSTRACT

BACKGROUND: To evaluate retinal and choroidal vascular changes in cases with hyphema after blunt ocular trauma that did not cause globe rupture or any retinal pathology. METHODS: This cross-sectional study included 29 patients who developed hyphema after unilateral blunt ocular trauma (BOT). The other healthy eyes of the same patients were evaluated as the control group. Optical coherence tomography-angiography (OCT-A) was used for imaging. In addition, choroidal parameters were compared by calculating the choroidal vascular index (CVI) and using choroidal thickness measurements by two independent researchers. RESULTS: Superior and deep flow values were significantly decreased in the traumatic hyphema group compared to the control group (p<0.05). Parafoveal deep vascular density (parafoveal dVD) values were decreased in traumatized eyes compared to control eyes (p=0.000). Vascular density values were similar other than that. In addition, there was a significant decrease in optic disc blood flow (ODF) and optic nerve head density (ONHD) values compared to the control group (p<0.05). In addition, no significant difference was observed between the groups in terms of mean CVI values (p>0.05). CONCLUSION: Non-invasive diagnostic tools such as OCTA and EDI-OCT can be used to detect and monitor early changes in retinal and choroidal microvascular flow in cases of traumatic hyphema.


Subject(s)
Eye Injuries , Photochemotherapy , Wounds, Nonpenetrating , Humans , Retinal Vessels/diagnostic imaging , Retinal Vessels/pathology , Fluorescein Angiography/methods , Hyphema/pathology , Cross-Sectional Studies , Photochemotherapy/methods , Photosensitizing Agents , Eye Injuries/complications , Eye Injuries/pathology , Tomography, Optical Coherence/methods , Wounds, Nonpenetrating/complications , Wounds, Nonpenetrating/pathology
3.
Sci Rep ; 13(1): 7767, 2023 May 12.
Article in English | MEDLINE | ID: mdl-37173401

ABSTRACT

Differential equations are the foundation of mathematical models representing the universe's physics. Hence, it is significant to solve partial and ordinary differential equations, such as Navier-Stokes, heat transfer, convection-diffusion, and wave equations, to model, calculate and simulate the underlying complex physical processes. However, it is challenging to solve coupled nonlinear high dimensional partial differential equations in classical computers because of the vast amount of required resources and time. Quantum computation is one of the most promising methods that enable simulations of more complex problems. One solver developed for quantum computers is the quantum partial differential equation (PDE) solver, which uses the quantum amplitude estimation algorithm (QAEA). This paper proposes an efficient implementation of the QAEA by utilizing Chebyshev points for numerical integration to design robust quantum PDE solvers. A generic ordinary differential equation, a heat equation, and a convection-diffusion equation are solved. The solutions are compared with the available data to demonstrate the effectiveness of the proposed approach. We show that the proposed implementation provides a two-order accuracy increase with a significant reduction in solution time.

4.
Photodiagnosis Photodyn Ther ; 42: 103323, 2023 Jun.
Article in English | MEDLINE | ID: mdl-36773755

ABSTRACT

BACKGROUND: We aimed to examine the changes in retinal, choroidal and optic nerve head vascular structures after Nd-YAG laser application due to posterior capsule opacification after cataract surgery by Optical coherence tomography angiography (OCTA). METHODS: Fifteen eyes of 15 patients who have posterior capsule opasification and underwent Nd-YAG laser capsulotomy were included in the study. OCTA imagings of patients were made before and one hour, one week and one month later after the laser procedure. RESULTS: No significant change was determined before and after capsulotomy in macular thickness measurements, flow areas and vessel densities (all p > 0.05). Optic nerve head vessel densities and flow areas didn't differ preoperatively and postoperatively (p > 0.05). CONCLUSIONS: Nd-YAG laser capsulotomy for posterior capsule opacification has no detectable effect on macular and optic nerve flows and vessel densities.


Subject(s)
Capsule Opacification , Laser Therapy , Lasers, Solid-State , Photochemotherapy , Humans , Capsule Opacification/surgery , Tomography, Optical Coherence/methods , Photochemotherapy/methods , Photosensitizing Agents , Retina , Angiography , Lasers, Solid-State/therapeutic use
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