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1.
Ear Nose Throat J ; 96(10-11): 419-432, 2017.
Article in English | MEDLINE | ID: mdl-29121374

ABSTRACT

Many techniques and graft materials have been used for the reconstruction of the tympanic membrane. We conducted a retrospective study to compare anatomic and functional outcomes of type 1 tympanoplasty that we performed with boomerang-shaped chondroperichondrial cartilage grafts (BSGs) and shield-shaped chondroperichondrial cartilage grafts (SSGs) in pediatric patients. Our study population was made up 121 patients-61 boys and 60 girls, aged 7 to 16 years (mean: 12.4)-who had undergone a type 1 tympanoplasty. Patients were divided into two groups according to the grafting technique used; there were 59 patients in the BSG group and 62 patients in the SSG group. Ear examinations were performed at postoperative months 3, 6, 12, and 24, and pure-tone average (PTA) for air-conduction threshold values and air-bone gaps (ABGs) were evaluated at 0.5, 1.0, 2.0, and 4.0 kHz at the same visits. We also investigated the impact of the graft material on functional graft success and intergroup differences (if any) in surgical success. Mean postoperative follow-up periods were 30.5 and 30.2 months in the BSG and SSG groups, respectively. We found that the success rates for tympanic membrane reconstruction were not significantly different in the two groups (91.5 and 88.7%). Postoperatively, the mean PTA and ABG values in both groups at 3, 6, 12, and 24 months were significantly lower than the preoperative values (p < 0.05). There were no significant differences in mean PTA values between the two groups at 3, 6, 12, and 24 months. However, the extent of the decrease in PTA values in the BSG group at 3 months was significantly greater than that of the SSG group (p < 0.05). There were no significant differences in mean ABG values between the two groups at 3, 6, and 12 months, but at 24 months, the value was significantly higher in the BSG group (p < 0.05). Finally, the extent of the decrease in ABG in the BSG group at both 3 and 6 months was significantly greater than that of the SSG group (p < 0.05). We conclude that the BSG procedure is a reliable and safe method of performing pediatric tympanoplasty.


Subject(s)
Cartilage/transplantation , Tympanic Membrane Perforation/surgery , Tympanoplasty/methods , Adolescent , Audiometry, Pure-Tone , Auditory Threshold , Bone Conduction , Child , Female , Humans , Male , Postoperative Period , Retrospective Studies , Treatment Outcome , Tympanic Membrane/surgery , Tympanic Membrane Perforation/physiopathology
2.
Kulak Burun Bogaz Ihtis Derg ; 25(3): 152-7, 2015.
Article in English | MEDLINE | ID: mdl-26050855

ABSTRACT

OBJECTIVES: This study aims to investigate the efficiency of mastoidectomy during tympanoplasty procedures in patients having sclerotic mastoid bone with dry or dried up tympanic cavity. PATIENTS AND METHODS: The study included 146 patients (66 males, 80 females; mean age 28.6 years; range 16 to 52 years) having sclerotic mastoid bone who underwent tympanoplasty between March 2010 and March 2013. Patients were divided into two groups: group A (34 males, 58 females; mean age 25.8 years; range 17 to 47 years) underwent only tympanoplasty, while tympanoplasty + mastoidectomy were performed on group B (32 males, 22 females; mean age 29.8 years; range 16 to 52 years). All outcomes were evaluated including the actual state of the tympanic membrane graft and level of hearing. RESULTS: While postoperative perforation and retraction rates were not significantly different between the two groups, results of group A were superior to group B in terms of operation duration and hearing results. CONCLUSION: Mastoidectomy is not an efficient procedure in chronic otitis media patients having sclerotic mastoid bone with dry or dried up tympanic cavity.


Subject(s)
Mastoid/surgery , Osteotomy/methods , Otitis Media/surgery , Otologic Surgical Procedures/methods , Adolescent , Adult , Chronic Disease , Female , Humans , Male , Mastoid/diagnostic imaging , Mastoid/pathology , Middle Aged , Otitis Media/diagnosis , Retrospective Studies , Sclerosis/diagnostic imaging , Sclerosis/pathology , Sclerosis/surgery , Tomography, X-Ray Computed , Treatment Outcome , Young Adult
3.
Kulak Burun Bogaz Ihtis Derg ; 25(2): 102-8, 2015.
Article in English | MEDLINE | ID: mdl-25935062

ABSTRACT

OBJECTIVES: This retrospective study aims to detect the prognostic factors which affect the duration of hospital stay and evaluate the complications which develop in patients with deep neck infection. PATIENTS AND METHODS: The study included 77 patients (40 males, 37 females; mean age 42.4±20.1 years; range 11 to 88 years) treated with a diagnosis of deep neck infection in our clinic between November 2006 and November 2012. Patients' demographic and clinical features were analyzed to detect their associations with development of complications and hospitalization time. RESULTS: Odontogenic origin and submandibular localization were the most frequently observed clinical appearance. Of eight patients (10.4%) who developed serious complications, two (2.6%) died. Age, comorbidity, presence of anemia alone, Ludwig's angina and retropharyngeal involvement were associated with increased rate of complications (p<0.05); while sex, antibiotic usage prior to admittance and primary location of infection were not related (p>0.05). Submandibular localization and absence of leucopenia reduced the risk of complications (p<0.05). The mean duration of hospital stay was 12.9±8.7 days (range 2-59 days). Age, presence of comorbidity and development of complications extended the hospitalization period (p<0.05). CONCLUSION: In spite of the improvements in diagnosis and treatment, deep neck infection may be an important cause of mortality if complications develop. Comorbid anemia, Ludwig's angina and retropharyngeal involvement were identified as the strongest predictors in terms of development of complications. Duration of hospital stay extended in patients who developed complications.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Fasciitis, Necrotizing/etiology , Ludwig's Angina/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Child , Fasciitis, Necrotizing/diagnosis , Fasciitis, Necrotizing/drug therapy , Female , Follow-Up Studies , Humans , Length of Stay/trends , Ludwig's Angina/complications , Ludwig's Angina/drug therapy , Male , Middle Aged , Neck , Retrospective Studies , Young Adult
4.
Case Rep Otolaryngol ; 2015: 813240, 2015.
Article in English | MEDLINE | ID: mdl-25878917

ABSTRACT

Intraoral spindle cell lipomas (SCL) are very rare and comprise ranging between 1.4%-9.8% of all intraoral lipomas. To our knowledge, no case of a SCL located on the soft palate has been reported in the English-language literature. A 31-year-old female was admitted with a swelling in her soft palate. On examination, a 3 cm sessile, nontender swelling was observed on her soft palate. After surgical excision, it was diagnosed as a SCL.

5.
Int J Pediatr Otorhinolaryngol ; 79(6): 808-811, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25843785

ABSTRACT

OBJECTIVES: To reveal the success of boomerang-shaped chondroperichondrial graft (BSCPG) in pediatric chronic otitis media cases. METHODS: A total of 43 pediatric patients (age 7-16 years) who had undergone type 1 tympanoplasty with the diagnosis of chronic otitis media between March 2010 and March 2013 were included in this retrospective study. The main outcome measures were the graft success rate and level of hearing improvement. RESULTS: Graft intake success rate was 90.7%. Mean preoperative and postoperative air-bone gap values were 20.51 ± 4.34 dB SPL and 9.32 ± 5.64 dB SPL, respectively (p < 0.001). Mean preoperative and postoperative pure tone average values were 28.6 ± 3.52 and 12.24 ± 5.22 respectively (p < 0.001). Air-bone gap was improved to ≤ 10 dB in 38 (88.37%) patients during the postoperative period. CONCLUSIONS: Boomerang-shaped chondroperichondrial grafting technique seems to be a successful alternative in the management of pediatric chronic otitis media cases. It has relatively higher grade graft success rate.


Subject(s)
Cartilage/transplantation , Otitis Media/surgery , Adolescent , Bone Conduction , Child , Chronic Disease , Female , Humans , Male , Retrospective Studies , Tympanoplasty
6.
Otolaryngol Head Neck Surg ; 147(5): 907-11, 2012 Nov.
Article in English | MEDLINE | ID: mdl-22753616

ABSTRACT

OBJECTIVE: To describe 2 subapproaches of the middle fossa approach: the transillumination method and transection of lines using the foramen spinosum, greater superficial petrosal nerve, and trigeminal impression to locate the malleus head for safe identification and decompression of the geniculate ganglion and facial nerve. STUDY DESIGN: Cadaver study. SETTING: A tertiary university hospital anatomy laboratory. SUBJECTS AND METHODS: The present study was conducted using 7 formalin-fixed cadaver heads (14 sides). A 0° endoscope was introduced into the external ear canal toward the posterosuperior quadrant of the tympanic membrane, after which transillumination was used to locate the malleus head. The brightest point indicated the convergence of the greater superficial petrosal nerve and a line drawn along the superior semicircular canal. An additional line was drawn parallel to the petrous ridge from the foramen spinosum and along the pathway of the greater superficial petrosal nerve. A third line connected the trigeminal impression to the zygomatic root. The area posterior to the intersection of these 2 lines separately with the third line was considered the zone of location of the malleus head. Among 17 patients undergoing surgery for facial paralysis between 1993 and 2011, transillumination was used in 6 patients to identify the malleus head to locate the geniculate ganglion. RESULTS: These techniques were proven to be reliable in locating the malleus head to find the geniculate ganglion in 14 dissected cadaveric temporal bones. CONCLUSION: Two methods of locating the malleus head for facial decompression were defined.


Subject(s)
Cranial Fossa, Middle/anatomy & histology , Decompression, Surgical/methods , Facial Paralysis/surgery , Cadaver , Facial Paralysis/etiology , Fractures, Bone/complications , Humans , Temporal Bone/injuries
7.
Int J Pediatr Otorhinolaryngol ; 76(1): 64-9, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22018731

ABSTRACT

OBJECTIVE: To investigate the histopathological changes and the expression of vascular endothelial growth factor (VEGF), inducible NO-synthase (iNOS), endothelial NO-synthase (eNOS), interleukin (IL)-1ß, and IL-17 in the rabbit middle ear mucosa after direct gastric content exposure. METHODS: Exploratory controlled study in which histological and immunochemical features were studied after gastric content-induced inflammation was established in rabbits. Sixteen healthy rabbits were divided into two equal groups. Gastric contents of an animal were injected into the middle ear of the same animal for 20 days. Saline was injected into the middle ear of the animals in the control group. The rabbits were humanely killed on day 27. Inflammation was assayed by light microscopy. Immunochemical staining was performed for VEGF, iNOS, eNOS, IL-1ß, and IL-17 expression. Experimental and control animals were examined using the same protocol. RESULTS: The expression levels of VEGF, iNOS, IL-1ß, and IL-17 differed significantly between the experimental and control groups (p=0.018, p=0.010, p=0.002, and p=0.002, respectively). The expression level of eNOS was not significantly different between the two groups (p=0.132). CONCLUSION: This study demonstrates that gastroesophagial reflux induced middle ear inflammation is associated with increased expression of VEGF, IL-1ß, IL-17, and iNOS.


Subject(s)
Interleukin-17/metabolism , Interleukin-1beta/metabolism , Nitric Oxide Synthase Type II/metabolism , Otitis Media/enzymology , Otitis Media/pathology , Vascular Endothelial Growth Factor A/metabolism , Animals , Biomarkers/metabolism , Biopsy, Needle , Disease Models, Animal , Gastric Juice , Immunohistochemistry , Male , Rabbits , Random Allocation , Sensitivity and Specificity
8.
Otolaryngol Head Neck Surg ; 146(3): 390-4, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22194242

ABSTRACT

OBJECTIVE: Head and neck squamous cell carcinomas readily metastasize to adjacent cervical lymph nodes. This is seen frequently in laryngeal squamous cell carcinoma (LSCC), and neck dissection may be performed in addition to excision of the primary lesion. The aim of this study was to define the frequency of level IIb metastasis to the lymph nodes in patients who underwent selective neck dissection because of LSCC. STUDY DESIGN AND SETTING: Cross-sectional study with planned data collection in a tertiary referral hospital. SUBJECTS AND METHODS: Eighty-one patients diagnosed with LSCC were accepted into the study. One hundred forty-eight neck dissection specimens were examined histopathologically, and those with level IIb metastasis were identified. The frequency of level IIb metastasis was evaluated in accordance with the primary tumor site, clinical N stage, central tumor presence, and T stage. RESULTS: Forty-seven of 81 patients were clinically N-, and 34 patients were clinically N+. Level IIb metastasis was seen in 5 (6%) of 81 patients, representing 5 of 148 neck dissection specimens. Two of these 5 patients were clinically N+ (6%), and 3 were clinically N- (6%). The relationship between level IIb metastasis and clinical N stage was not statistically significant (P ≥ .05). Likewise, no statistically significant relationships between the other parameters and level IIb involvement were found. CONCLUSION: Level IIb nodal involvement is very rare in LSCC. Therefore, the area can generally be preserved in elective neck dissection to lessen morbidity and, specifically, to avoid damaging the function of the spinal accessory nerve.


Subject(s)
Carcinoma, Squamous Cell/secondary , Laryngeal Neoplasms/pathology , Laryngeal Neoplasms/surgery , Lymphatic Metastasis/pathology , Neck Dissection/methods , Adult , Aged , Combined Modality Therapy , Cross-Sectional Studies , Disease-Free Survival , Female , Follow-Up Studies , Frozen Sections , Humans , Laryngeal Neoplasms/mortality , Laryngectomy/methods , Laryngectomy/mortality , Lymph Node Excision/methods , Lymph Node Excision/mortality , Male , Middle Aged , Neck Dissection/mortality , Neck Dissection/statistics & numerical data , Neoplasm Invasiveness/pathology , Neoplasm Staging , Postoperative Complications/epidemiology , Postoperative Complications/pathology , Prospective Studies , Risk Assessment , Survival Analysis , Treatment Outcome
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