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Clin Nucl Med ; 49(2): e68-e69, 2024 Feb 01.
Article in English | MEDLINE | ID: mdl-38170920

ABSTRACT

ABSTRACT: Medication-related osteonecrosis of the jaw (ONJ) is rare adverse effect of zoledronic acid. We present ONJ detected in a 65-year-old man with prostate cancer who underwent 18 F-FDG PET/CT for metabolic characterization and to exclude a second primary malignancy of the liver lesion observed in 68 Ga-PSMA PET/CT. ONJ has high metabolic activity on 18 F-FDG PET/CT and no PSMA receptor activation on the 68 Ga-PSMA PET/CT. In this case, we wanted to underline the importance of 18 F-FDG PET/CT imaging of medication-related ONJ in patients receiving zoledronic acid therapy and to emphasize that rapid and appropriate treatment can be provided.


Subject(s)
Osteonecrosis , Prostatic Neoplasms , Male , Humans , Aged , Positron Emission Tomography Computed Tomography/methods , Fluorodeoxyglucose F18 , Zoledronic Acid , Radiopharmaceuticals , Gallium Radioisotopes , Prostatic Neoplasms/complications , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology
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