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1.
Cureus ; 15(11): e48530, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38074023

ABSTRACT

Background In adhesive dentistry, creating a long-lasting bond between resin composite and dentin is crucial. The durability of this bond dramatically depends on the structural integrity of collagen fibrils present in the hybrid layer. However, matrix metalloproteinases (MMPs) can degrade collagen fibrils, compromising the bond's longevity. Aim The objective is to evaluate the potential effectiveness of natural extracts from Moringa and Centella in preventing collagen degradation caused by MMPs. Material and methods The phenol and flavonoid content of the extracts were evaluated. Dentin beams were demineralized and pre-treated with 1% or 5% Moringa, 1% or 5% Centella, or 2% chlorhexidine (CHX) (five minutes), with untreated beams as control. Beams were incubated in calcium- and zinc-containing media (CM) at pH 7.2 and 37°C for one, 10, 20, and 30 days, and C-terminal cross-linked telopeptide of type I collagen (ICTP) release (collagen telopeptide) was assessed using an enzyme-linked immunosorbent assay (ELISA) kit after 30 days. Results Data were analyzed with a one-way analysis of variance (ANOVA). All test groups showed a different dry mass loss. The control group had the highest loss, followed by CHX, with the least loss in the 5% Moringa and Centella groups. ICTP release ranged from 1.781 ± 0.319 to 3.146 ± 0.684, with 5% Moringa showing the most negligible release. Conclusion The group that received 5% Moringa exhibited the most effective reduction in collagen degradation compared to all the other groups.

2.
Heliyon ; 9(6): e17274, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37360095

ABSTRACT

Globally, the demand for energy from renewable sources is growing due to the increasing electricity consumption and the pollution of fossil fuels. The government has framed various policies to facilitate green energy generation, encouraging renewable energy source usage through PV installations in multiple sectors, including educational institutions. The primary objective of this paper is to propose a methodological approach for analysing the performance of the installed PV system on the rooftop of a university building in Tamil Nadu, India. The site selected is favourable for electricity generation from PV systems with an average global solar radiation of 5.82 kWh/m2day. Solar energy changes periodically with annual and daily variations and is not steady due to seasonal changes. The step-by-step performance assessment and the annual performance of the 100-kW solar PV system, which was instituted in 2019, with the forecasted parameters, are presented in this paper. Therefore, the assessment analysis is carried out in four phases: feasibility assessment, Energy yield assessment, Life cycle assessment, and Power quality assessment. To improve the solar PV output and efficiency, considering the solar irradiation, temperature, wind velocity, etc., PV yield is measured to evaluate the PV system's energy metrics. This paper also considers the carbon credits earned, solar power generated in the location, and the payback period. The power quality assessment is carried out in this paper to test the PV plant's compliance with effective grid integration.

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