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1.
Comput Intell Neurosci ; 2022: 8787023, 2022.
Article in English | MEDLINE | ID: mdl-35634063

ABSTRACT

In the past few years, remote monitoring technologies have grown increasingly important in the delivery of healthcare. According to healthcare professionals, a variety of factors influence the public perception of connected healthcare systems in a variety of ways. First and foremost, wearable technology in healthcare must establish better bonds with the individuals who will be using them. The emotional reactions of patients to obtaining remote healthcare services may be of interest to healthcare practitioners if they are given the opportunity to investigate them. In this study, we develop an artificial intelligence-based classification system that aims to detect the emotions from the input data using metaheuristic feature selection and machine learning classification. The proposed model is made to undergo series of steps involving preprocessing, feature selection, and classification. The simulation is conducted to test the efficacy of the model on various features present in a dataset. The results of simulation show that the proposed model is effective enough to classify the emotions from the input dataset than other existing methods.


Subject(s)
Artificial Intelligence , Delivery of Health Care , Emotions , Humans , Machine Learning
2.
Int J Neurosci ; 112(8): 965-82, 2002 Aug.
Article in English | MEDLINE | ID: mdl-12448837

ABSTRACT

The isoprenoid pathway produces digoxin, an endogenous membrane Na(+)-K+ ATPase inhibitor and regulator of neurotransmitter transport. The objective of the study was to relate digoxin status and hemispheric dominance to the pathogenesis of psychiatric disorders--bipolar mood disorder, major depressive disorder, and schizophrenia. The following parameters were assessed in bipolar mood disorder during the manic phase and depressive phase of the illness as well as in major depressive disorder, and schizophrenia: HMG CoA reductase activity, tryptophan and tyrosine catabolic patterns, red blood cell (RBC) Na(+)-K+ ATPase activity, and serum magnesium. These parameters were compared to individuals of differing hemispheric dominance. The levels of serum digoxin and HMG CoA reductase activity were found to be decreased in the depressive phase of bipolar mood disorder and major depressive disorder with a corresponding increase in RBC Na(+)-K+ ATPase activity and serum magnesium levels. There was increase in tyrosine and tyrosine catabolites, and a reduction in tryptophan and its catabolites, in the serum in the depressive phase of bipolar mood disorder and major depressive disorder. The neurotransmitter patterns and digoxin levels in the depressive phase of bipolar mood disorder/major depressive disorder correlated with those in right-handed/left hemisphere dominant individual. The neurotransmitter patterns and digoxin levels in the manic phase of bipolar mood disorder and schizophrenia correlated with those in left-handed/right hemisphere dominant individuals. Digoxin status and hemispheric dominance could correlate with the pathogenesis of psychiatric disorders--schizophrenia, major depressive disorder, and bipolar mood disorder.


Subject(s)
Bipolar Disorder/metabolism , Depressive Disorder, Major/metabolism , Dominance, Cerebral , Schizophrenia/metabolism , Sodium-Potassium-Exchanging ATPase/metabolism , Adult , Bipolar Disorder/physiopathology , Depressive Disorder, Major/physiopathology , Digoxin/blood , Humans , Hydroxymethylglutaryl CoA Reductases/metabolism , Magnesium/blood , Sampling Studies , Schizophrenia/physiopathology , Tryptophan/metabolism , Tyrosine/metabolism
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