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1.
Rev Esp Enferm Dig ; 77(6): 433-6, 1990 Jun.
Article in Spanish | MEDLINE | ID: mdl-2223252

ABSTRACT

We describe an experimental model of acute pancreatitis in conscious rats, based on biliary reflux; sodium deoxycholate was injected while maintaining the common duct (biliary and pancreatic) temporally occluded. A progressive increase of serum amylase, cardiac rate and hematocrit value, as well as a decrease of plasma proteins are characteristic of this experimental model. Blood pressure was maintained until shortly before death, which occurred after 85 minutes. This is a simple model, reliable and reproducible, which requires minimal surgical manipulation.


Subject(s)
Pancreatitis/physiopathology , Acute Disease , Animals , Common Bile Duct/physiology , Deoxycholic Acid , Disease Models, Animal , Male , Pancreatitis/chemically induced , Rats , Rats, Inbred Strains
2.
Rev Esp Enferm Apar Dig ; 76(5): 495-7, 1989 Nov.
Article in Spanish | MEDLINE | ID: mdl-2616862

ABSTRACT

Isolated obstruction of the splenic vein leads to the appearance of a relatively uncommon form of portal hypertension, the diagnosis of which depends on a high rate of awareness, and it can be successfully treated by splenectomy. A case is described of segmental portal hypertension, with special emphasis on the difficulty of its diagnosis and the measures used. Therapeutic possibilities are commented.


Subject(s)
Gastrointestinal Hemorrhage/etiology , Hypertension, Portal/complications , Stomach Diseases/etiology , Constriction, Pathologic/complications , Humans , Hypertension, Portal/etiology , Male , Middle Aged , Splenic Vein
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