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1.
PLoS One ; 18(10): e0292172, 2023.
Article in English | MEDLINE | ID: mdl-37812613

ABSTRACT

Cancer is a serious public health concern worldwide and is the leading cause of death. Blood cancer is one of the most dangerous types of cancer. Leukemia is a type of cancer that affects the blood cell and bone marrow. Acute leukemia is a chronic condition that is fatal if left untreated. A timely, reliable, and accurate diagnosis of leukemia at an early stage is critical to treating and preserving patients' lives. There are four types of leukemia, namely acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic in extracting, and chronic myelogenous leukemia. Recognizing these cancerous development cells is often done via manual analysis of microscopic images. This requires an extraordinarily skilled pathologist. Leukemia symptoms might include lethargy, a lack of energy, a pale complexion, recurrent infections, and easy bleeding or bruising. One of the challenges in this area is identifying subtypes of leukemia for specialized treatment. This Study is carried out to increase the precision of diagnosis to assist in the development of personalized plans for treatment, and improve general leukemia-related healthcare practises. In this research, we used leukemia gene expression data from Curated Microarray Database (CuMiDa). Microarrays are ideal for studying cancer, however, categorizing the expression pattern of microarray information can be challenging. This proposed study uses feature selection methods and machine learning techniques to predict and classify subtypes of leukemia in gene expression data CuMiDa (GSE9476). This research work utilized linear programming (LP) as a machine-learning technique for classification. Linear programming model classifies and predicts the subtypes of leukemia Bone_Marrow_CD34, Bone Marrow, AML, PB, and PBSC CD34. Before using the LP model, we selected 25 features from the given dataset of 22283 features. These 25 significant features were the most distinguishing for classification. The classification accuracy of this work is 98.44%.


Subject(s)
Hematologic Neoplasms , Leukemia, Myeloid, Acute , Humans , Transcriptome , Programming, Linear , Leukemia, Myeloid, Acute/diagnosis , Leukemia, Myeloid, Acute/genetics , Bone Marrow
2.
Sensors (Basel) ; 22(19)2022 Sep 28.
Article in English | MEDLINE | ID: mdl-36236476

ABSTRACT

The teeth are the most challenging material to work with in the human body. Existing methods for detecting teeth problems are characterised by low efficiency, the complexity of the experiential operation, and a higher level of user intervention. Older oral disease detection approaches were manual, time-consuming, and required a dentist to examine and evaluate the disease. To address these concerns, we propose a novel approach for detecting and classifying the four most common teeth problems: cavities, root canals, dental crowns, and broken-down root canals, based on the deep learning model. In this study, we apply the YOLOv3 deep learning model to develop an automated tool capable of diagnosing and classifying dental abnormalities, such as dental panoramic X-ray images (OPG). Due to the lack of dental disease datasets, we created the Dental X-rays dataset to detect and classify these diseases. The size of datasets used after augmentation was 1200 images. The dataset comprises dental panoramic images with dental disorders such as cavities, root canals, BDR, dental crowns, and so on. The dataset was divided into 70% training and 30% testing images. The trained model YOLOv3 was evaluated on test images after training. The experiments demonstrated that the proposed model achieved 99.33% accuracy and performed better than the existing state-of-the-art models in terms of accuracy and universality if we used our datasets on other models.


Subject(s)
Deep Learning , Stomatognathic Diseases , Tooth , Humans , Radiography, Panoramic , X-Rays
3.
Sensors (Basel) ; 23(1)2022 Dec 28.
Article in English | MEDLINE | ID: mdl-36616911

ABSTRACT

Anomalous driving behavior detection is becoming more popular since it is vital in ensuring the safety of drivers and passengers in vehicles. Road accidents happen for various reasons, including health, mental stress, and fatigue. It is critical to monitor abnormal driving behaviors in real time to improve driving safety, raise driver awareness of their driving patterns, and minimize future road accidents. Many symptoms appear to show this condition in the driver, such as facial expressions or abnormal actions. The abnormal activity was among the most common causes of road accidents, accounting for nearly 20% of all accidents, according to international data on accident causes. To avoid serious consequences, abnormal driving behaviors must be identified and avoided. As it is difficult to monitor anyone continuously, automated detection of this condition is more effective and quicker. To increase drivers' recognition of their driving behaviors and prevent potential accidents, a precise monitoring approach that detects abnormal driving behaviors and identifies abnormal driving behaviors is required. The most common activities performed by the driver while driving is drinking, eating, smoking, and calling. These types of driver activities are considered in this work, along with normal driving. This study proposed deep learning-based detection models for recognizing abnormal driver actions. This system is trained and tested using a newly created dataset, including five classes. The main classes include Driver-smoking, Driver-eating, Driver-drinking, Driver-calling, and Driver-normal. For the analysis of results, pre-trained and fine-tuned CNN models are considered. The proposed CNN-based model and pre-trained models ResNet101, VGG-16, VGG-19, and Inception-v3 are used. The results are compared by using the performance measures. The results are obtained 89%, 93%, 93%, 94% for pre-trained models and 95% by using the proposed CNN-based model. Our analysis and results revealed that our proposed CNN base model performed well and could effectively classify the driver's abnormal behavior.


Subject(s)
Automobile Driving , Deep Learning , Problem Behavior , Accidents, Traffic/prevention & control , Safety
4.
Sensors (Basel) ; 21(23)2021 Dec 03.
Article in English | MEDLINE | ID: mdl-34884099

ABSTRACT

Diabetes is a fatal disease that currently has no treatment. However, early diagnosis of diabetes aids patients to start timely treatment and thus reduces or eliminates the risk of severe complications. The prevalence of diabetes has been rising rapidly worldwide. Several methods have been introduced to diagnose diabetes at an early stage, however, most of these methods lack interpretability, due to which the diagnostic process cannot be explained. In this paper, fuzzy logic has been employed to develop an interpretable model and to perform an early diagnosis of diabetes. Fuzzy logic has been combined with the cosine amplitude method, and two fuzzy classifiers have been constructed. Afterward, fuzzy rules have been designed based on these classifiers. Lastly, a publicly available diabetes dataset has been used to evaluate the performance of the proposed fuzzy rule-based model. The results show that the proposed model outperforms existing techniques by achieving an accuracy of 96.47%. The proposed model has demonstrated great prediction accuracy, suggesting that it can be utilized in the healthcare sector for the accurate diagnose of diabetes.


Subject(s)
Algorithms , Diabetes Mellitus , Diabetes Mellitus/diagnosis , Fuzzy Logic , Humans
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