ABSTRACT
Objetivo: Evaluar la fiabilidad y validez de un cuestionario de calidad de vida en pacientes con cáncer de vejiga no músculo invasivo. Materiales y métodos: Se incluyeron 180 pacientes. Se elaboró un cuestionario de 21 preguntas agrupadas en 5 áreas que los pacientes cumplimentaban. A su vez, los pacientes cumplimentaban el cuestionario Functional Assessment of Cancer Therapy- Bladder Cancer (FACT-BL). Para estudiar la fiabilidad se calculó el coeficiente Alfa de Cronbach y el Índice Kappa. Para estudiar la validez de criterio se estudió, con el coeficiente de correlación de Pearson, la asociación entre las puntuaciones obtenidas por el nuevo cuestionario y el FACT-BL. Para estudiar la validez de constructo (factorial y discriminante) se realizó análisis factorial, comparándose con la «t» de Student, las puntuaciones según características tumorales objetivas de peor calidad de vida (por ejemplo localización en trígono). Resultados: El Alfa de Cronbach fue 0,83 y los Índices Kappa oscilaron entre 0,7 y 1. En el estudio de asociación del nuevo cuestionario y FACT-BL se obtuvo una r = 0,82 para la puntuación global, y entre una r = 0,68 (enfermedad) y una r = 0,97 (vida sexual) en las diferentes dimensiones. En el análisis factorial se obtuvo KMO = 0,77 y test de Barlett p < 0,001. La comparación de las puntuaciones en presencia o ausencia de determinadas características tumorales han obtenido peores resultados de calidad de vida en presencia de las mismas, en la mayoría de ocasiones, estadísticamente significativas (p < 0.05). Conclusión: El cuestionario elaborado para medir la calidad de vida de los pacientes con cáncer de vejiga no músculo invasivo es fiable y válido
Objective: To determine the reliability and validity of a quality-of-life survey for patients with nonmuscle-invasive bladder cancer. Material and methods: A total of 180 patients were included in the study. We developed a survey with 21 questions grouped into 5 areas. The patients filled in this survey and the Functional Assessment of Cancer Therapy - Bladder Cancer (FACT-BL) survey. To assess reliability, we calculated Cronbach's alpha coefficient and the kappa index. To determine criterion validity, we studied the association between the scores obtained from our survey and those from the FACT-BL survey using the Pearson correlation coefficient. To determine the construct validity (factorial and discriminatory), we performed a factor analysis, comparing it with Student's t-test for the scores obtained according to the tumour characteristics of reduced quality of life (e.g., malignancies located at the trigone of the bladder). Results: Cronbach's alpha reliability coefficient was .83, and the kappa index varied between .7 and 1. For the association study between the new survey and the FACT-BL survey, we measured an r = .82 for the overall score and between r = .68 (disease) and r = .97 (sex life) in the various measures. In the factor analysis, we measured a Kaiser-Meyer-Olkin index of .77 and performed the Barlett test (P < .001). The comparison between the scores, in the presence or absence of certain tumour characteristics, has shown a reduced quality of life when those characteristics are present, which was statistically significant (P < .05) in the majority of cases. Conclusion: Our survey to measure the quality of life of patients with nonmuscle-invasive bladder cancer is reliable and valid
Subject(s)
Humans , Aged, 80 and over , Urinary Bladder Neoplasms/diagnosis , Quality of Life , Self Concept , Neoplasm Invasiveness , Reproducibility of ResultsABSTRACT
OBJECTIVE: To determine the reliability and validity of a quality-of-life survey for patients with nonmuscle-invasive bladder cancer. MATERIAL AND METHODS: A total of 180 patients were included in the study. We developed a survey with 21 questions grouped into 5 areas. The patients filled in this survey and the Functional Assessment of Cancer Therapy - Bladder Cancer (FACT-BL) survey. To assess reliability, we calculated Cronbach's alpha coefficient and the kappa index. To determine criterion validity, we studied the association between the scores obtained from our survey and those from the FACT-BL survey using the Pearson correlation coefficient. To determine the construct validity (factorial and discriminatory), we performed a factor analysis, comparing it with Student's t-test for the scores obtained according to the tumour characteristics of reduced quality of life (e.g., malignancies located at the trigone of the bladder). RESULTS: Cronbach's alpha reliability coefficient was .83, and the kappa index varied between .7 and 1. For the association study between the new survey and the FACT-BL survey, we measured an r=.82 for the overall score and between r=.68 (disease) and r=.97 (sex life) in the various measures. In the factor analysis, we measured a Kaiser-Meyer-Olkin index of .77 and performed the Barlett test (P<.001). The comparison between the scores, in the presence or absence of certain tumour characteristics, has shown a reduced quality of life when those characteristics are present, which was statistically significant (P<.05) in the majority of cases. CONCLUSION: Our survey to measure the quality of life of patients with nonmuscle-invasive bladder cancer is reliable and valid.
