[The accuracy of the imaging procedures (sonography, MRT, CT, angio-CT,nuclear medicine) in characterizing liver tumors]. / Treffsicherheit bildgebender Verfahren (Sonographie, MRT, CT, Angio-CT, Nuklearmedizin) bei der Charakterisierung von Lebertumoren.

In a prospective study, an attempt was made to determine the specificity of various imaging methods for defining tumours of the liver rather than their ability to demonstrate them. It was based on 130 patients with histologically confirmed lesions (33 haemangiomas, 17 FNH, 4 hepatocellular adenomas, 28 HCC, 36 adenocarcinoma metastases). The methods were MRT (130 cases), sonography (119), CT (122), dynamic arterial angio-CT (15), 99TC-EHIDA or blood pool scintigraphy (4 FNH, haemangiomas, HCC, 44 cases). MRT showed somewhat better results (accuracy 80%) than CT (73%) and angio-CT (73%) in demonstrating the type of lesion. The results of scintigraphy (53%) and sonography (69%) were rather worse. The range of accuracy for MRT, CT and sonography varied from 94% (haemangiomas with MRT) to 47% (FNH with sonography).

[Perinatal imaging diagnosis in twin pregnancies with humanus amorphus]. / Perinatale bildgebende Diagnostik bei Geminischwangerschaften mit Humanus amorphus.

The humanus amorphus or acardiac twin is a very rare anomaly found only in monocygotic multiple pregnancies. In 8 twin pregnancies observed from 1977 to 1988 at the Charité-Hospital the findings of perinatal imaging diagnostics (sonography, amniofetrography, postnatal radiography) have been presented. For the prenatal diagnosis, especially for continuous prenatal control in these high-risk pregnancies, sonography seems to be the suitable method. However, an exact classification and morphological description of such monstrosities will be possible only by postnatal radiography (eventually in combination with a transumbilical angiography). Six ouf of eight cases were classified as an acephalous type, and two as an acardius anceps fetus.

[Indications for roentgenologic diagnosis of the colon in gynecology]. / Indikationen zur röntgenologischen Kolondiagnostik in der Gynäkologie.

X-ray barium-enema examination of the colon recently is an established method in gynecology performed as differential or spreading diagnosis. In 276 patients the results of 291 barium-enema examinations have been analysed retrospectively. The radiographic findings correlate 279 times with the intraoperative and histologic diagnoses (165 correct nonpathologic and 114 correct pathologic). On the basis of the obtained correct and false diagnoses, common indications for using irrigoscopy in gynecology have been suggested. In this context, abdominal and/or vaginal sonography as well as sigmoidoscopy are suitable methods which should be applicated compulsorily before radiologic examination of the colon in women suffering from gynecologic diseases.

[Diagnostic imaging in female infertility and sterility--desiderata and reality]. / Bildgebende Diagnostik bei weiblicher Infertilität und Sterilität--Wunsch und Realität.

For medical imaging in the pelvic region in female infertility/sterility several methods of investigation are available. Risk/benefit-considerations of the mentioned methods lead to a diagnostic gold-standard: Hysterosalpingography, laparoscopy, laparotomy. Hysteroscopy and sonography can be employed facultatively after hysterosalpingography.

[The normal fetal intestinal tract in correlation to gestational age. An amniofetography study]. / Der normale fetale Intestinaltrakt in Abhängigkeit vom Gestationsalter. Eine amniofetographische Studie.

Amniofetography represents an adequate method to study prenatally the fetal gastrointestinal tract in utero. In 108 pregnancies without fetal intestinal anomalies, the course of intestinal growth with regard to the lumen of certain parts of intestine has been analyzed. The results agree with those of other authors using sonography to study the intrauterine development of fetal intestinal tract. The demonstrated kinetics of contrast media passage through the gastrointestinal tract, following its intra-amnion application, contribute the knowledge of normal fetal physiology.

[Ultrasound diagnosis of severe fetal abnormalities]. / Ultrasonographisch diagnostizierte schwere fetale Missbildung.

Reported in this paper is a case of premature termination of pregnancy in the 29th week because of sonographically diagnosed multiple malformations of the fetus. Holoprosencephaly, omphalocele, polyspleny syndrome, double-outlet right ventricle, and several skeletal malformations were established by pathologico-anatomic investigations. Possible correlation between these malformations are discussed in some details.

[Detection and evaluation of data in perinatal diagnosis using a personal computer]. / Erfassung und Auswertung von Daten perinataler Diagnostik mittels "personal computer".

Imaging, biochemical, genetic, clinical, histological, cytological and morphological examinations methods are practised in perinatal diagnostics. We propose a system of data registration and processing using a personal computer regarding both prenatal therapeutic measures. Data are collected as data store "perinatal diagnostic" which may be expanded prospectively at any time.

[Results of invasive and pharmacosonographic studies in pregnancy (II: Amniofetography)]. / Ergebnisse invasiver und pharmakosonographischer Untersuchungen in der Schwangerschaft (II. Mitteilung: Amniofetographie).

Prenatal diagnosis of fetal diseases and malformations, using invasive techniques is outlined in this paper. The value of amniofetography under present conditions is discussed together with the use of drugs both isolated and in conjunction with fill-up of the amniotic cavity. Indications for puncture of fluid-filled body cavities, with reference being made to patients looked after at the Humboldt-University Berlin, School of Medicine (Charité), Department of Gynaecology and Obstetrics, from 1985 up to 1987, are reported, too.

[Results of invasive and pharmacosonographic studies in pregnancy (I)]. / Ergebnisse invasiver und pharmakosonographischer Untersuchungen in der Schwangerschaft (I. Mitteilung).

In prenatal diagnosis besides radiographic methods there is a growing trend towards the use of invasive diagnostic techniques. These techniques have proved to be suitable for early detection of genetically determined conditions, diseases, and malformations of different origin. Invasive examination techniques were applied to 1.104 cases of prenatal diagnosis at Humboldt-University, Berlin, School of Medicine (Charité), Department of Gynaecology and Obstetrics, from January 1st, 1985, up to September 30th, 1987. In this paper importance and possible applications of these methods have been reported.

[Perinatal medicine study group. Diagnosis and therapy of ventral schistasis]. / Arbeitsgruppe "Perinatal-Medizin". Diagnose und Therapie ventraler Spaltbildungen.

Reported in this paper are twelve cases of ventral schistasis transferred for cooperative prenatal assessment, diagnosis, and therapy to the Berlin Charité Hospital of Gynaecology and Obstetrics in 1985 and 1986. Concomitant malformations were recorded from eight in ten omphaloceles. Three of these children were delivered on full term by spontaneous parturition or caesarean section. They were surgically treated immediately after birth. Gastroschisis was recorded from two pregnancies with ventral schistasis. No generally valid recommendation can be given for approach to ventral schistasis. The approach should rather be interdisciplinary and should be preceded by careful diagnosis. Parents should be involved in decision-making.

[Modification of the spectrum of neonatal surgery by prenatal diagnosis]. / Die Beeinflussung des Spektrums der Neugeborenenchirurgie durch die pränatale Diagnostik.

Expansion of prenatal diagnosis will alter the spectrum of neonatal surgery. The ethos of the medical profession calls for decision in favour of the mother, whenever evidence can be produced to the effect that a severely damaged or nonviable foetus may endanger the health of the pregnant woman. Humanistically and legally warranted termination of pregnancy in such cases will reduce the number of severely malformed newborns on whom nothing can be done but palliative treatment. Early detection of foetal diseases will enable, on the other hand, well-timed preparation of acutely necessary life-saving interventions and will bring down the rate of emergency operations on newborns.