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Singapore Med J ; 48(11): 1042-6, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17975695

ABSTRACT

Multifocal involvement of the skeleton is extremely rare, with tuberculous pyomyositis and tenosynovitis of the wrist being uncommon presentations of skeletal tuberculosis (TB). We present an immunocompetent 68-year-old woman with concomitant presentation of these uncommon forms of extrapulmonary TB heralded by tuberculous pyomyositis. Tuberculous pyomyositis can often masquerade as malignancy, leading to misdiagnosis and patients being mistakenly referred to oncologists for management. This delayed the institution of appropriate drug therapy. Similarly, because of its rarity, tuberculous tenosynovitis may be overlooked as a cause of chronic tenosynovitis. In the absence of pathognomonic imaging findings, the diagnosis ultimately rests on histopathological and microbiological confirmation. This case highlights the importance of maintaining a high index of suspicion of the protean manifestations of extrapulmonary TB, not only in high-risk populations, but in immunocompetent individuals as well. It also illustrates the advantage of a clinically-directed multidisciplinary approach in early recognition and treatment of this entity.


Subject(s)
Metacarpophalangeal Joint , Muscle Neoplasms/diagnosis , Pyomyositis/diagnosis , Tenosynovitis/diagnosis , Thigh , Thumb , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis/diagnosis , Aged , Antitubercular Agents/therapeutic use , Bacteriological Techniques , Biopsy, Needle , Combined Modality Therapy , Diagnosis, Differential , Drug Therapy, Combination , Female , Humans , Magnetic Resonance Imaging , Metacarpophalangeal Joint/pathology , Muscle Neoplasms/drug therapy , Muscle Neoplasms/pathology , Muscle, Skeletal/pathology , Muscle, Skeletal/surgery , Polymerase Chain Reaction , Pyomyositis/drug therapy , Pyomyositis/pathology , Pyomyositis/surgery , Tenosynovitis/drug therapy , Tenosynovitis/pathology , Tenosynovitis/surgery , Thigh/surgery , Thumb/pathology , Thumb/surgery , Tuberculosis/drug therapy , Tuberculosis/pathology , Tuberculosis/surgery , Tuberculosis, Osteoarticular/drug therapy , Tuberculosis, Osteoarticular/pathology , Tuberculosis, Osteoarticular/surgery
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