[The role of the urology nurse in prehabilitation and same-day discharge robot-assited radical prostatectomy programs]. / Le rôle de l'IDE dans l'éducation thérapeutique avant opération et la mise en place d'un programme de prostatectomie totale robotique en ambulatoire.

INTRODUCTION: The purpose of this article is to explain the role of urology nurse in prehabilitation and same-day discharge programs for robotic radical prostatectomy. METHODS: This article is based on the analysis of the literature and the experience of our center. RESULTS: In order to prepare patients for outpatient surgery, urology nurse plays a key role during prehabilitation journeys. Two weeks before the operation, the healthcare teams (nurses, anesthetists, physiotherapists, etc.) organize workshops to explain to patients the operation course and post-operative care in order to allay any anxieties. Individual and group interviews, in specific workshops (compression stockings, urinary catheter, sexology) are organized in particular with urology nurse to answer all patients' questions. In association with enhanced recovery after surgery pathway, these programs improve the patient experience and satisfaction as well as peri-operative outcomes, and allows the development of an outpatient surgery program which currently represents approximately one third of surgeries. CONCLUSION: The implementation of perioperative protocols including prehabilitation improves the early results of robotic total prostatectomy, but also the patient experience. The urology nurse has a key role to play during these patient education days and in the preparation, information, support and follow-up of the patient, since the prehabilitation journey until the patient leaves the outpatient clinic.

Síntomas musculoesqueléticos en la perimenopausia / Musculoskeletal symptons turing perimenopause

La menopausia espontánea queda establecida al transcurrir 12 meses consecutivos de amenorrea sin otra causa aparente y por lo tanto sólo puede reconocerse de manera retrospectiva. Alrededor de la menopausia, algunas mujeres presentan síntomas osteoarticulares, generalmente autolimitados. Se dispone de pocos estudios realizados en la población general y la mayoría se han llevado a cabo en mujeres sintomáticas o que proceden de unidades de menopausia, lo cual conlleva una sobreestimación de la prevalencia de los síntomas. En nuestro entorno no se dispone de estudios poblacionales que valoren la prevalencia de síntomas climatéricos. Objetivo: Determinar si existe relación entre los síntomas musculoesqueléticos y la menopausia, caracterizando a las mujeres entre los 40 y los 55 años. Material y métodos: Los datos fueron recolectados a través de una encuesta y pertenecen a 60 mujeres entre 40 y 55 años de edad, asistidas en los consultorios de reumatología, ginecología y medicina general del sector público y privado de la ciudades de Neuquén y Gral. Roca durante 4 meses del año 2005, excluyéndose aquellas con afecciones reumáticas previamente diagnosticadas. Resultados: De las 60 pacientes encuestadas, encontramos dolor osteoarticular en el 68.3% del total. La frecuencia de presentación del dolor aumenta proporcionalmente con la edad. De las 41 pacientes que presentan dolor, la mayor frecuencia corresponde a las mujeres menopáusicas (35%). La localización preferente de los dolores fueron los miembros superiores (manos, hombros, codos y muñecas). Observamos correlación entre el dolor y el incremento del índice de masa corporal (IMC). No registramos diferencias en la manifestación dolorosa entre aquellas mujeres que realizan actividad física y las que no la hacen. Conclusiones: El dolor osteoarticular es más frecuente en mujeres que NO menstrúan. El dolor es más notable en miembros superiores y en aquellas pacientes que tienen execeso de peso.

[Family violence and adolescence]. / Violences intrafamiliales et adolescence.

Intrafamilial violence represents a vast topic, even if one limits the subject to the nuclear family. Indeed it includes violence from parents to the child, violence between brothers and sisters, conjugal violence and violence exercised by the child to his parents. Although one can differentiate the types of violence (physical, sexual, and psychological), they often coexist within the same family. Adolescence favors the onset or the reactivation of familial violence; this violence often has repercussion on the psychological equilibrium of the adolescent. Very little is written about parents abused by one of their children (usually an adolescent). This phenomenon is relatively unrecognized and its frequency probably under-estimated. It points to a distortion in parent to child relationship. Therapeutic and/or socio-educational approach must be directed toward both the victim and the aggressor.

Cast 'headed' post-cores to resist fracture of endodontically treated anterior teeth.

A method has been presented that minimizes coronal fracture of endodontically treated anterior teeth. Preparation of the headed post-core is practical because the techniques uses readily available materials and equipment.

Influence of food on the absorption of metoprolol administered as an Oros drug delivery system to man.

The influence of food on the release, absorption and metabolism of metoprolol has been studied after single administration of a 19/190 Oros system to eight healthy volunteers on four occasions, once after an overnight fast, and just before each of three daily meals (breakfast, lunch and dinner). The plasma concentration-time profiles under the four test conditions were virtually identical, and no statistically significant differences in mean areas under the curves between 0 and 32 h, peak concentrations, or times to peak, were detected. The absorption of metoprolol was unaffected by food intake, with 80-90% of the amount absorbed reaching the systemic circulation within 10 h. The ratios of areas under the curve for alpha-hydroxymetoprolol to its parent drug were in the same range for the four treatments, and similar to those reported after conventional tablets. The in vivo release and absorption of drug from the Oros system and its systemic availability, were not influenced by concomitant ingestion of food.

Determination of metoprolol and its alpha-hydroxylated metabolite in human plasma by high-performance liquid chromatography.

A high-performance liquid chromatographic method has been developed for the simultaneous determination of metoprolol and its alpha-hydroxylated metabolite in plasma, Metoprolol, alpha-hydroxymetoprolol and alprenolol (internal standard) are extracted from plasma at alkaline pH with diethyl ether-dichloromethane (4:1, v/v) and back-extracted with 0.01 N sulfuric acid. A 100-microliter volume of the acidic extract is injected into the chromatographic system. The compounds are eluted in about 12 min with acetonitrile-acetate buffer (75:25, v/v) on a LiChrosorb RP-8 (5 micron) column. The quantitative determinations are made fluorometrically. Concentrations down to 35 nmol/1 (10 ng/ml) of metoprolol base and 30 nmol/1 (8 ng/ml) of alpha-hydroxymetoprolol base in plasma can be determined with good precision and accuracy.

Porcelain surface characterization and staining in the office.

Chairside custom staining and characterization of porcelain can influence significantly the quality of porcelain restorations and dentist-patient relationships. Technical guidelines have been presented to assist the dentist.

Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.

The chromatographic behaviour of some cephalosporins as a function of pH and ionic strength of the mobile phase was studied on 10-microns LiChrosorb RP-18. Acidic cephalosporins were retained longest in their neutral form with an acidic eluent. Amphoteric cephalosporins were retained longest in their protonated form with an acidic eluent of low ionic strength. Cefotiam was retained longer with an alkaline mobile phase. LiChrosorb RP-18, Nucleosil C18 and muBondapak C18 gave rise to different selectivities when an acidic eluent, methanol-water (25:75) containing 0.2% of 1.8 M H2SO4 was used. This may be related to interactions with residual silanol groups. The studied cephalosporins (with the exception of cefotiam and cefsulodin) were separated from compounds present in biological fluids on 5-microns LiChrosorb RP-18 using the mobile phase 0.2% of 1.8 M H2SO4 in a mixture of methanol and water with various methanol contents. The determination of cefotiam in biological fluids was performed with an alkaline mobile phase. The preparation of the sample was simple and rapid: precipitation of plasma proteins or dilution of urine. The method was applied to the determination of ceftizoxime in human plasma and urine. Concentrations down to 0.2 micrograms/ml of plasma and 25 micrograms/ml of urine could be determined with good reproducibility and accuracy.

Plastic stopping--update.

Dura Seal powder and liquid and Dura Lay liquid acrylic resin materials have many uses. Methods for using these acrylic resin materials for copings, functionally generated paths, fitting crowns to clasps, centric relation stops, temporary fixed partial dentures, and porcelain additions have been described.

GLC determination of carbamazepine suitable for pharmacokinetic studies.

A GLC determination of carbamazepine in plasma and urine is described. It is performed by injecting the cyano derivative, which, in contrast to carbamazepine, has bood GLC properties. The method is suitable for pharmacokinetic studies, since it is specific and accurate down to 0.27 mug/ml.