ABSTRACT
BACKGROUND: Clear cell carcinoma of the ovary (CCC) is a rare variety of ovarian cancer. CASE: A case of CCC in a 49-year-old woman was diagnosed in asciticfluid on thin-layer preparations. Peritoneal fluid cytology revealed papillary clusters of cells with clear cytoplasm and extracellular hyaline material generally without neoplastic cells. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. CONCLUSION: CCC has a distinctive cytomorphologic appearance, and the entity may be diagnosed on ascitic fluid cytology.
Subject(s)
Adenocarcinoma, Clear Cell/diagnosis , Ascites/etiology , Ascites/pathology , Ovarian Neoplasms/diagnosis , Adenocarcinoma, Clear Cell/complications , Female , Humans , Middle Aged , Ovarian Neoplasms/complications , Tomography, X-Ray ComputedABSTRACT
Se presenta un caso de carcinoma peritoneal primario extraovárico. Este raro e interesante tumor se caracteriza por una carcinomatosis peritoneal y por un patrón histológico similar al del carcinoma papilar seroso de ovario, pero sin comprometer o sólo afectando microscópicamente la superficie de los ovarios. La paciente presentaba hinchazón abdominal, ascitis con citología positiva y el CA-125 elevado en el suero. En el momento de la cirugía se encontró una afectación peritoneal difusa o multifocal, existiendo afectación microscópica de la superficie serosa ovárica. Las células tumorales fueron positivas para citoqueratina (AE1/AE3), antígeno de membrana epitelial, B72.3, Ber- EP4, Leu-M1, p53, antígeno carcinoembrionario, fosfatasa alcalina placentaria, proteína S-100, CA-125 y receptores estrogénicos
One case of extraovarian primary peritoneal carcinoma is reported. This rare interesting tumor is characterized by a peritoneal carcinomatosis with ascites and by a histological pattern similar to ovarian serous papillary carcinoma, but it either spares the ovaries or involves the surface of the ovaries only microscopically. The patient had abdominal swelling, ascites with positive cytology, and elevated serum CA-125. At surgery multifocal or diffuse peritoneal involvement was found. Microscopic ovarian serosal surface involvement was demonstrated. Tumor cells stained positive for cytokeratin (AE1/AE3), epithelial membrane antigen, B72.3, Ber-EP4, Leu-M1, p53, carcinoembryonic antigen, placental alkaline phosphatase, S-100, CA-125, and estrogen receptors
Subject(s)
Female , Aged , Humans , Carcinoma, Papillary/pathology , Peritoneal Neoplasms/pathology , Ovarian Neoplasms/pathology , Biomarkers, Tumor , Alkaline Phosphatase , Alkaline Phosphatase/genetics , Carcinoma, Papillary/diagnosis , Immunohistochemistry/methods , Peritoneal Neoplasms/diagnosis , Ovarian Neoplasms/diagnosisABSTRACT
BACKGROUND: Primary pulmonary botryomycosis is an uncommon suppurative bacterial infection of the lung. Cytologic findings by conventional methods and thin-layer preparations in1 case are presented. CASE: A 45-year-old man had primary pulmonary botryomycosis diagnosed by fine needle aspiration cytology (FNAC). Aspiration smears were characterized by densely packed microorganisms surrounded by polymorphonuclear leukocytes. Microbiologic analysis of cytologic material revealed colonies of Streptococcus constellatus. CONCLUSION: FNAC diagnosis of pulmonary botryomycosis offers the opportunity to distinguish this bacterial infection from lung cancer and avoid unnecessary surgery.
Subject(s)
Lung Neoplasms/pathology , Lung/pathology , Pneumonia, Bacterial/pathology , Streptococcal Infections/pathology , Streptococcus constellatus/isolation & purification , Biopsy, Fine-Needle , Diagnosis, Differential , Humans , Lung/microbiology , Male , Middle Aged , Pneumonia, Bacterial/microbiology , Streptococcal Infections/microbiologyABSTRACT
Presentamos un caso de linfoma primario cutáneo de células grandes CD30 (Ki-1) positivo con características histológicas que recuerdan a un sarcoma epitelioide. El linfoma primario cutáneo anaplásico de células grandes CD30 positivo es una entidad clinicopatológica recientemente descrita, reconocida por criterios inmunohistoquímicos. Describimos el caso de una mujer de 74 años de edad con un tumor ulcerado en el tronco, de 3 meses de evolución. El diagnóstico se hizo en base a los hallazgos inmunohistoquímicos. No se detectó afectación sistémica. La paciente está bien, sin enfermedad extracutánea concurrente, tras 6 años de seguimiento. Los estudios clínicos indican un mejor pronóstico en los linfomas cutáneos anaplásicos de células grandes CD30 positivos que en los linfomas anaplásicos de células grandes CD30 positivos nodales y que en los otros linfomas cutáneos anaplásicos de células grandes. Este es pues, un caso de regresión espontánea y seguimiento favorable en este tipo de linfomas cutáneos, que tiene unos rasgos morfológicos peculiares, como es su parecido morfológico con un sarcoma epitelioide (AU)
Subject(s)
Aged , Female , Humans , Lymphoma, Large-Cell, Anaplastic/pathology , Diagnosis, Differential , BiopsyABSTRACT
BACKGROUND: Dermal analogue tumor of the salivary gland is a rare form of salivary gland adenoma. Cytologic and histologic findings of 1 case are presented. CASE: A 74-year-old-female had a dermal analogue tumor in the parotid gland diagnosed by fine needle aspiration cytology (FNAC). Aspiration smears were characterized by aggregates of uniform epithelial cells, and cell groups bordered on thick, basement membrane-like material. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. CONCLUSION: Dermal analogue tumor of the salivary gland has a distinctive cytomorphologic appearance, and diagnosis of this neoplasm by FNAC is possible. Preoperative FNAC of salivary gland lesions is important in planning the most appropriate type of treatment.
Subject(s)
Adenoma/pathology , Parotid Gland/pathology , Parotid Neoplasms/pathology , Aged , Basement Membrane/pathology , Biomarkers, Tumor/metabolism , Biopsy, Fine-Needle , Diagnosis, Differential , Epithelial Cells/pathology , Female , Humans , Hyalin/metabolism , Immunohistochemistry , Predictive Value of Tests , Reproducibility of ResultsABSTRACT
BACKGROUND: Extramedullary plasmacytoma (EMP) of the breast is extremely rare, especially that not associated with multiple myeloma. CASE: A case of plasmacytoma of the breast in a 73-year-old man was diagnosed by fine needle aspiration cytology (FNAC). Aspiration smears revealed a dispersed population of plasmacytoid cells at various stages of maturation. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. CONCLUSION: FNAC diagnosis of plasmacytoma of the breast offers the opportunity to distinguish these neoplasms from primary mammary tumors and avoid unnecessary surgery.
Subject(s)
Bone Marrow Neoplasms/pathology , Breast Neoplasms, Male/secondary , Plasma Cells/pathology , Plasmacytoma/secondary , Aged , Antineoplastic Agents/pharmacology , Biomarkers, Tumor/metabolism , Biopsy, Fine-Needle , Diagnosis, Differential , Humans , Male , Mastectomy , Multiple Myeloma/pathologyABSTRACT
BACKGROUND: Liposarcomatous differentiation within a phyllodes tumor is extremely rare. Cytologic and histologic findings of a case of malignant phyllodes tumor with liposarcomatous stroma of the breast are presented. CASE: A 45-year-old female had a malignant phyllodes tumor with pleomorphic liposarcomatous stroma diagnosed by fine needle aspiration (FNA) cytology. The cytologic findings were representative of the histologic features. CONCLUSION: Malignant phyllodes tumor of the breast can be diagnosed by FNA. It is very important to acknowledge the morphologic variants of sarcomatous stroma and to recognize the cytologic features of such rare tumors to prevent misdiagnosis as primary sarcomas of the breast. Preoperative diagnosis is important in planning the most appropriate type of treatment. It is also important to follow patients for long periods for recurrence and metastasis after surgery for this tumor.
