ABSTRACT
Mucinous tubular and spindle cell carcinomas (MTSCC) are low-grade renal epi-thelial neoplasms with approximately 100 documented cases reported in the literature. We report a case of MTSCC in a 79-year-old patient in association with a renal tuberculosis infection that has never been reported. Further investigations are needed to determine the frequency and true prognosis of these tumors.
Subject(s)
Adenocarcinoma, Mucinous/complications , Kidney Neoplasms/complications , Tuberculosis, Renal/complications , Adenocarcinoma, Mucinous/pathology , Adenocarcinoma, Mucinous/surgery , Aged , Biopsy , Humans , Immunohistochemistry , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Magnetic Resonance Imaging , Male , Neoplasm Staging , NephrectomyABSTRACT
INTRODUCTION: Congenital epulis (CE) of the newborn also known as congenital granular cell tumor or Neumann tumor is an uncommun benign tumour occuring in the anterior alveolar ridge of the jaws. It may interfer with breathing and feeding. In our study, we discuss the clinicopathologic and evolutive caracteristics and the diagnosis problems of this entity. OBSERVATION: A newborn girl, two months old, presented at birth a nodular mass in the upper alveolar crete of the maxilla. The mass measured 1.5 cm and exhibited a smooth surface. Histologically, it was composed of diffuse sheets and clusters of granular cells with abundant coarsely granular cytoplasm. The evolution was good without recurrence after five months. DISCUSSION: CE is a rare tumor; its etiopathogenesis is still unclear. The diagnosis suspected clinically is confirmed by the histopathological study. The prognosis is exellent without recurrence.
Subject(s)
Gingival Neoplasms/pathology , Echocardiography , Fatal Outcome , Female , Genetic Counseling , Gingival Neoplasms/genetics , Homozygote , Humans , Infant , Infant, Newborn , Lung/pathology , Male , Mutation , Polymerase Chain Reaction/methods , Pulmonary Alveolar Proteinosis/diagnostic imaging , Pulmonary Alveolar Proteinosis/genetics , Pulmonary Alveolar Proteinosis/pathology , Pulmonary Surfactant-Associated Protein B/deficiency , RNA, Messenger/genetics , Radiography, ThoracicSubject(s)
Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis , Prostatic Diseases/etiology , Aged, 80 and over , Antigens, CD/analysis , Antigens, CD20/analysis , Cell Division , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Leukemia, Lymphocytic, Chronic, B-Cell/radiotherapy , Male , Prostate-Specific Antigen/analysis , Prostatic Diseases/pathologyABSTRACT
BACKGROUND: Polymorphous low-grade adenocarcinoma (APBG) is a variant of malignant tumour of minor salivary glands usually arising in the palate. AIM: Our aim is to discuss morphology, evolution and differential diagnosis of this rare tumour. CASE REPORTS: The first case interested a 65-year-old-woman admitted for a two-months-history of a right submaxillary swelling. Examination found a tumour of the right side of the palate. A biopsy concluded to a pleomorphic adenoma. Giving that the mass enlarged, a surgical resection carrying off the thyroid with a bilateral neck dissection was performed. Diagnosis was an APBG partially resected with lymph node metastasis. The patient received adjuvant radiotherapy. Local recurrence appeared 28 months after treatment. The second case interested a 57-year-old-woman who consulted for a 12-year-history of a swelling of the lower lip. Clinical examination showed a painless nodule measuring 2 cm located in the mucosal side of the lower lip. An excisional biopsy was performed. Pathologic examination concluded to an APBG completely resected. The patient had no evidence of disease with a follow-up of 54 months. CONCLUSION: APBG is characterised by a morphologic diversity and a cytologic uniformity that may cause a diagnostic dilemma especially with adenoid cystic carcinoma and pleomorphic adenoma. Its aggressiveness is assessed by its local infiltrative growth pattern requiring a wide surgical excision.
