1.
Chem Commun (Camb)
; 50(87): 13300-3, 2014 Nov 11.
Article
in English
| MEDLINE
| ID: mdl-25227948
ABSTRACT
Both convergent and divergent strategies for the synthesis of "onion peel" glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.
Subject(s)
Dendrimers/chemistry , Dendrimers/chemical synthesis , Glycerides/chemistry , Glycerides/chemical synthesis , Dendrimers/pharmacology , Glycerides/pharmacology , Lectins/chemistry , Ligands , Molecular Structure , Pseudomonas aeruginosa/chemistry , Virulence Factors/antagonists & inhibitors
2.
J Org Chem
; 76(2): 724-7, 2011 Jan 21.
Article
in English
| MEDLINE
| ID: mdl-21190367
ABSTRACT
Original glycodendrimers emanating from propargylated hexaphenylbenzene cores and containing up to 54 peripheral sugar ligands have been synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using both convergent and divergent approaches.
