Effect of induced acute mild arterial hypertension on postoperative analgesic requirements after laparoscopic ovarian cystectomy: a randomized double blinded study.

Objective: To evaluate the effectiveness of inducing acute hypertension during laparoscopic ovarian cystectomy on postoperative nalbuphine analgesic requirements. Methods: The total dose of nalbuphine used in the hypertension group was significantly lower than that in the control group (p <0.001). The VAS score was significantly lower in the hypertension group on arrival to PACU and during the period between 1 and 6 hours postoperatively. Results: The total dose of nalbuphine used in the hypertension group was significantly lower than that in the control group (p <0.001). The VAS score was significantly lower in the hypertension group on arrival to PACU and during the period between 1 and 6 hours postoperatively. Conclusion: This study demonstrates that pharmacologically induced mild acute intraoperative hypertension significantly reduces postoperative nalbuphine consumption and pain scores following laparoscopic ovarian cystectomy. Trial registration in Pan African Clinical Trial Registry: identification number for the registry is PACTR201508001247179.