ABSTRACT
The molluscicidal activity of saponins isolated from the plant Anagallis arvensis (Primulaceae) was studied against schistosome intermediate hosts, Biomphalaria glabrata and Oncomelania quadrasi. @Strong molluscicidal activity was found in two compounds called desglucoanagalloside B and anagalloside B. Their structures were identified on the basis of chemical and spectroscopic analyses and their activities are comparable to that of the synthetic molluscicide, niclosamide.
Subject(s)
Biomphalaria/drug effects , Mollusca/drug effects , Molluscacides/chemistry , Oleanolic Acid/analogs & derivatives , Plants, Medicinal/chemistry , Saponins/chemistry , Schistosoma , Triterpenes , Animals , Magnetic Resonance Spectroscopy , Models, Chemical , Mollusca/parasitology , Niclosamide/chemistry , Niclosamide/pharmacology , Saponins/pharmacology , Spectrometry, Mass, Fast Atom BombardmentABSTRACT
BACKGROUND: Khite (also known as fatlah in Egypt) is a manual technique of temporary vellus hair removal that is widely performed in the Middle East. METHODS: The technique of khite is reviewed as illustrated. RESULTS: Khite is an effective method of removing unwanted vellus hairs. CONCLUSIONS: Dermatologists in all parts of the world should be familiar with khite, because the ease of international travel may bring patients to their attention who have khite-association complications such as erythema, folliculitis, and secondary pigmentary changes.
