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Arch Pharm (Weinheim) ; 324(6): 349-51, 1991 Jun.
Article in English | MEDLINE | ID: mdl-1763945

ABSTRACT

Heterocycles containing the indole ring system include some novel pharmacologically active compounds. Isatin and its N-acetylisatin are extremely versatile intermediates in the construction of a variety of heterocyclic systems when reacted with thiosemicarbazide derivatives. Literature survey revealed various interesting reactions of thiocarbohydrazide with cyclic ketones, cyclic 1,2-diketones and isatin.


Subject(s)
Anti-Infective Agents/chemical synthesis , Hydrazines/chemistry , Isatin/chemistry , Anti-Bacterial Agents , Bacteria/drug effects , Fungi/drug effects , Hydrazines/pharmacology , Indicators and Reagents , Isatin/pharmacology , Microbial Sensitivity Tests
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