1.
Acta Pharm
; 62(2): 191-200, 2012 Jun.
Article
in English
| MEDLINE
| ID: mdl-22750817
ABSTRACT
Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.