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1.
Clin Case Rep ; 12(5): e8886, 2024 May.
Article in English | MEDLINE | ID: mdl-38707603

ABSTRACT

Key Clinical Message: Non-lupus full house nephropathy is a rare entity that is still poorly understood. It can complicate post-transplant kidneys and result in a de novo process. Treatment is difficult but can be possibly achieved with optimization of immune suppression. Abstract: Non-lupus full house nephropathy is a rare entity with an unclear incidence. It describes the kidney biopsy findings of positive deposits for IgG, IgA, IgM, C3, and C1q on immunofluorescence in the absence of the classical diagnostic features of systemic lupus nephritis. This disease entity is becoming more recognized but further studies are still needed to evaluate the incidence, etiologies, and management of this condition. Transplant glomerulopathy is a major cause for renal graft loss. It can present with a wide variety of manifestations; it can cause AKI, CKD, or glomerular inflammations through an immune complex or autoimmune-mediated damage.

2.
Clin Case Rep ; 9(4): 2317-2322, 2021 Apr.
Article in English | MEDLINE | ID: mdl-33936686

ABSTRACT

Saphenous vein graft aneurysm is an uncommon condition and knowledge about its natural history, and a multi-specialty heart team approach is of utmost importance for better clinical outcomes. This case highlights importance of percutaneous intervention as a viable therapeutic option in the case of saphenous vein graft aneurysms.

3.
Cardiooncology ; 6(1): 31, 2020 Dec 14.
Article in English | MEDLINE | ID: mdl-33308287

ABSTRACT

Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.

4.
JBJS Case Connect ; 10(1): e0266, 2020.
Article in English | MEDLINE | ID: mdl-32224686

ABSTRACT

CASE: We describe the case of an 85-year-old woman who presented with worsening right hip pain after a conversion hip replacement. Subsequent imaging demonstrated a gas-containing collection in the lateral thigh. She was taken to the operating room for irrigation and debridement, where intraoperative cultures returned positive for Clostridium difficile. Surgical management was followed by a prolonged course of antibiotics. CONCLUSIONS: Clostridium difficile as the etiology of infection in a conversion arthroplasty is exceedingly rare. Orthopaedic surgeons and infectious disease specialists should consider C. diff as a potential cause of infection in conversion hip arthroplasty because management options will need to be tailored.


Subject(s)
Arthroplasty, Replacement, Hip/adverse effects , Clostridioides difficile/isolation & purification , Clostridium Infections/etiology , Surgical Wound Infection/microbiology , Aged, 80 and over , Clostridium Infections/diagnostic imaging , Clostridium Infections/surgery , Female , Hip Fractures/surgery , Humans , Surgical Wound Infection/diagnostic imaging , Surgical Wound Infection/surgery
5.
BMJ Case Rep ; 12(12)2019 Dec 29.
Article in English | MEDLINE | ID: mdl-31888895

ABSTRACT

In the setting of severe septic shock, a 70-year-old woman had an ST segment myocardial infarction with ST elevations in the inferolateral leads. On cardiac catheterisation, no obstructive pathology was noted. Chest imaging revealed a large mediastinal mass measuring 8.5×6.5×7.5 cm in the visceral compartment of the mediastinum, with contrast enhancement from the right coronary artery (RCA). A biopsy was preformed and cytology was consistent with a well-differentiated neuroendocrine neoplasm. On review of the cardiac catherisation, it was noted that the mass was deriving blood supply from the RCA. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a rare but well-documented phenomenon. In this case, MINOCA was caused by coronary steal syndrome in the setting of profound hypotension. Immediate management is with haemodynamic support; there is no role for coronary intervention.


Subject(s)
Coronary Vessels/pathology , Mediastinal Neoplasms/pathology , Neuroendocrine Tumors/pathology , ST Elevation Myocardial Infarction/physiopathology , Shock, Septic/etiology , Aged , Biopsy, Fine-Needle/methods , Bronchoscopy/methods , Chemoradiotherapy/methods , Computed Tomography Angiography/methods , Coronary Angiography/methods , Coronary Vessels/diagnostic imaging , Electrocardiography/methods , Female , Humans , Mediastinal Neoplasms/diagnostic imaging , Myocardial Infarction/etiology , Myocardial Infarction/physiopathology , Neuroendocrine Tumors/blood supply , Neuroendocrine Tumors/complications , Neuroendocrine Tumors/therapy , Shock, Septic/diagnosis , Treatment Outcome
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