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1.
Pol Merkur Lekarski ; 45(269): 192-194, 2018 Nov 28.
Article in Polish | MEDLINE | ID: mdl-30531668

ABSTRACT

The patient was diagnosed with chronic hepatitis B at 19 years old. Biochemical, serological and histopathological diagnostic processes were followed by pegylated interferon treatment. After 24 weeks of therapy treatment was discontinued due to pathological thyroid hormones values. The patient was diagnosed with Hashimoto's thyroiditis and levothyroxine therapy initiated. Over the following two years, the patient was not under hepatology specialist care. She was admitted to the Clinic due to a high aminotransferase level and concomitant pruritus in the 32nd week of her first pregnancy. In the end the patient was diagnosed as having an exacerbation of chronic hepatitis B. After recognition of high HBV (hepatitis B virus) viremia, treatment with tenofovir was initiated. In the course of treatment the following were observed: HBeAg/anti-Hbe (antigen HBe/anti-HBe antibodies) seroconversion, decrease in viral load, biochemical normalization; and an improvement in clinical status of the patient was obtained. An elective caesarean section was performed in week 40; the new-born received 10 points on the Apgar scale. During the first hours of life, the passive-active immunoprophylaxis: immunoglobulin and the first dose of anti-HBV vaccine, were given to the new-born. Over long-term observation it was found that there was no vertical transmission of the hepatitis B virus to the child.


Subject(s)
Cesarean Section , Hepatitis B, Chronic/prevention & control , Infectious Disease Transmission, Vertical/prevention & control , Female , Humans , Infant, Newborn , Pregnancy
2.
Przegl Epidemiol ; 61(1): 67-71, 2007.
Article in Polish | MEDLINE | ID: mdl-17702441

ABSTRACT

UNLABELLED: Prevalence and clinical manifestation of borreliosis were analyzed. Evaluation of frequency of anti-Borrelia burgdorferi in sera collected from forestry workers were performed too. MATERIALS AND METHODS: 113 forestry workers from Kujawsko-Pomorskie voivodeship were examined (56 from Szubin district, 29 from Runowo district and 28 from Lutówko district). Duration of works, frequency of exposition for tick, presence of erythema migrans (EM) in the past and present manifestation of Lyme disease were analyzed. Serological studies were performed in each case. RESULTS: Duration of works balanced between one and 47 years. In 92 cases exposition took place more than one time. 24 suffered from EM in the past but only two of them were treated with antibiotics because of this manifestation. 14 of 113 patients suffered from Lyme arthritis. Serological markers of infection with B.b. were finding in 37 cases. CONCLUSIONS: (1) Not every infection with B.b. are clinically manifested. (2) The risk of infection with B.b. is higher in patient frequently exposed on ticks. (3) There is no correlation between duration of works in a forest and frequency of B.b. infection in forestry workers what indicate that infected with B.b. ticks expanded on kujawsko-pomorskie voivodeship recently. (4) Forestry workers should be systematically examined because of high risk of Lime disease. (5) The information about borreliosis should be widespread.


Subject(s)
Antibodies, Bacterial , Borrelia burgdorferi/immunology , Forestry , Lyme Disease/epidemiology , Lyme Disease/immunology , Occupational Diseases/epidemiology , Adult , Aged , Antibodies, Bacterial/blood , Female , Humans , Lyme Disease/blood , Male , Middle Aged , Occupational Diseases/virology , Occupational Exposure , Poland/epidemiology , Prevalence
3.
Wiad Lek ; 59(3-4): 274-6, 2006.
Article in Polish | MEDLINE | ID: mdl-16813279

ABSTRACT

This work presents a case of Q fever in a 55-year-old man who came back from Lebanon. The dominant symptoms of the disease were fever and dry cough and in physical testing fine rales at the bottom of the right lung. An epidemiologic investigation (a monthly stay in Lebanon) and a serologic testing (indirect immunofluorescence assay) were useful to confirm a diagnosis of Q fever. Moreover the authors of the work paid attention to the differential diagnosis of Q fever and effectiveness of tetracycline in the treatment. The basic methods of the prevention of the disease were also described. In the case of a fever in individuals coming back from the region of the Mediterranean Sea Q fever should be taking into consideration in the differential diagnosis.


Subject(s)
Q Fever/diagnosis , Q Fever/drug therapy , Travel , Anti-Bacterial Agents/therapeutic use , Coxiella burnetii/growth & development , Diagnosis, Differential , Fluorescent Antibody Technique, Indirect , Humans , Male , Middle Aged , Tetracycline/therapeutic use
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