ABSTRACT
Palladium-catalyzed organic reactions are ubiquitous due to their high efficiency in coupling reactions and have wide applications in synthetic chemistry. Their widespread use in organic synthesis has been attributed to moderate conditions associated with reactions and tolerance to different types of functional groups. Palladium-catalysts are extensively used in aminocarbonylation of aryl halides for the synthesis of amides and have found a wide variety of applications in pharmaceuticals, agrochemicals, petrochemicals, materials, polymers, etc. In this review, we summarize the recent advances in the synthesis of amides via palladium-catalyzed aminocarbonylation of aryl halides, and cover literature from 2010 to 2021.
ABSTRACT
Pyrazole and its derivatives have gained wide attention in pharmaceutical, agrochemical and biological fields as well as in industry. They exhibit various biological activities such as anti-pyretic, anti-microbial, anti- inflammatory, anti-tumor, anti-viral, anti-histaminic, anti-convulsant, fungicidal, insecticidal, etc. In this review, we summarise the recent advances in the synthesis of pyrazole derivatives using various methodologies and covers literature from 2017-2020.
