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Med Tr Prom Ekol ; (6): 32-5, 2012.
Article in Russian | MEDLINE | ID: mdl-22997757

ABSTRACT

Experimental studies helped to reveal ultrastructural changes in hepatocytes, caused by prolonged exposure to heavy metals salts taken in combination and ratios characteristic to soil contents near Almalyk mining and smelting enterprise. The authors demonstrated possibility of liver structural recovery via enterosorption with additional antioxidant therapy.


Subject(s)
Antioxidants/therapeutic use , Enterosorption/methods , Liver/drug effects , Liver/ultrastructure , Metals, Heavy/toxicity , Soil Pollutants/toxicity , Animals , Antioxidants/administration & dosage , Chemical and Drug Induced Liver Injury/metabolism , Chemical and Drug Induced Liver Injury/pathology , Chemical and Drug Induced Liver Injury/prevention & control , Hepatocytes/drug effects , Hepatocytes/metabolism , Hepatocytes/ultrastructure , Lipid Peroxidation/drug effects , Liver/metabolism , Microscopy, Electron, Transmission , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , Rats , Salts , Time Factors
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