ABSTRACT
OBJECTIVES: The aim of this study was to examine the presence of antimicrobial resistance / susceptibility strains of Escherichia coli in inpatients and outpatients. MATERIALS AND METHODS: It is a retrospective study carried out at the Department of Microbiology, Parasitology and Virology Faculty of Medicine, University of Sarajevo. In cooperation with the Microbiological laboratory of the Cantonal Hospital Zenica and the Microbiological laboratory of the General Hospital Tesanj, 3863 urine samples were processed in the period from March 1st to March 31st 2016. RESULTS: Our study showed that E. coli had the highest antimicrobial resistance to trimethoprim / sulfamethoxazole (38.61%), followed by amoxicillin / clavulanic acid (19.62%), ciprofloxacin (9.49%), gentamicin (8.86%), cephalexin (8.23%), nitrofurantoin (8.23%), cefuroxime (7.52%), ceftazidime (6.33%), cefuroxime (89.87%), amikacin (4.43%). CONCLUSIONS: The isolated strains of E. coli showed the highest resistance to trimethoprim / sulfamethoxazole and amoxicillin / clavulanic acid. The isolated strains of E. coli showed the greatest susceptibility to amikacin and ceftazidime. Gender distribution of positive E. coli isolates showed statistically significant differences in favor of females.
ABSTRACT
AIM: To analyze usefulness of measurement amino-terminal pro-B type natriuretic peptide of (NT pro-BNP) as the one of parameters of water overload in patients with chronic kidney diseases. METHODS: A total number of 277 patients with chronic kidney diseases (CKD) were followed up in the period often years between January 2000 and July 2010. Patients with creatinine clearance of 60 ml/min or less were included in the study. Changes of creatinine clearance, and in last five years changes of NT pro-BNP were followed. Water overload was analyzed using chest x-ray in relation with concentration of NT pro-BNP in the blood. RESULTS: Decrease of clearance of creatinine ranged from average 54.7 ml/min in the first year to 14.6 ml/min in the fifth year of the monitoring. Average NT pro-BNP level in patients without any sign of water overload was 94 pg/ml (SD 21), mean value in those with Kerley lines was 231 pg/ml/L (SD 64), in those with clear signs of water overload but without pleural effusion it was 525 pg/ml (SD 223), and in those with water retention including pleural effusion it was 1606 pg/ml (SD 1134). Using test of multiple correlation a statistically significant correlation between X-ray signs of water overload and NT pro-BNP concentration was shown, p < 0.05. CONCLUSION: Measurement of NT pro-BNP was increased in the beginning of water overload in patients with CKD. Increased value of NT pro-BNP may be found earlier than any other signs of water overload. NT pro-BNP was a useful parameter in estimation of water overload in these patients.
Subject(s)
Kidney Diseases/metabolism , Natriuretic Peptide, Brain/blood , Peptide Fragments/blood , Water-Electrolyte Imbalance/diagnosis , Biomarkers/blood , Body Water/metabolism , Chronic Disease , Creatinine/analysis , Female , Humans , Kidney Diseases/complications , Male , Middle Aged , Uric Acid/blood , Water-Electrolyte Imbalance/complications , Water-Electrolyte Imbalance/etiologyABSTRACT
In the paper are stated the data of ten years observations of the occurrences of the seroconversion in the patients at the dyalized treatment in the dyalized center in Tesanj. The seropositiveness to B and C hepatitis was 16.5%, what is the usual percentage for the local population. The serconversion to the positive C hepatitis occurred in one patient, and that in the first year of the dialyzed treatment, what remains the possibility the dyalizis began in the period of the incubation. The separation of the seropositive apparati for the dyalisisi from the rest made the sufficient organizational measure by the dyalized center.
