[The lipid composition and aggregating capacity of thrombocytes in hyper- and hypothyroidism]. / Lipidnyi sostav i agregatsionnaia sposobnost' trombotsitov pri giper- i gipotireoze.

The aim of the work was to investigate the phospholipid composition and parameters of platelet aggregation in patients with hypo- and hyperthyroidism. The data obtained have shown that phospholipid liposomes added exogenously, changed the function of cell hemostasis and, in particular, decreased platelet aggregation. Unlike the other phospholipids, phosphatidylinositol, cardiolipin and phosphatidylserine produced the most significant effect on this index and corrected, to a certain extent, disturbed platelet functions in hypothyroidism.

[Partial blocking of the organofaction of iodine with thyroglobulin antibodies]. / Chastichnoe blokirovanie organofikatsii ioda tireoglobulinovymi antitelami.

The influence is studied of purified thyroglobulin antibodies on a stage of thyroid hormone formation, i.e. iodine organofication, using a method of inorganic iodine replacement by potassium perchlorate. A decreased marker uptake by the thyroid and a delay of iodide inclusion into organic components were observed after incubation of rat thyroid slices and injection of a similar antiserum to normal rats 24 hours before radioactive iodine administration. The data obtained indicate that the disturbance of iodine organofication is possible under thyroglobulin antibody effect, accompanied by the thyroid autoimmune process development.