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A novel regiospecific N to O-methyl transferase activity in the biotransformation of a thebaine derivative with Cunninghamella echinulata NRRL 1384.
Abel, Anthony M; Allan, Graham R; Carnell, Andrew J; Davis, J Alf.
Chem Commun (Camb) ; (16): 1762-3, 2002 Aug 21.
Article in English | MEDLINE | ID: mdl-12196987

ABSTRACT

A novel regiospecific N- to O-methyl transfer reaction has been characterised in the biotransformation of an N-CD3-thebaine derivative with the fungus Cunninghamella echinulata NRRL 1384.


Subject(s)
Cunninghamella/metabolism , Thebaine/metabolism , Transferases/metabolism , Biotransformation , Cunninghamella/enzymology , Deuterium , Fermentation , Methylation , Substrate Specificity
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