ABSTRACT
We discuss an extremely unusual presentation of a 19-month-old child with cor triatriatum and an intact interatrial septum, who presented for the first time at the age of 16 months with wheezing and repeated lower respiratory tract infections. At surgery, a thick fibromuscular membrane with a 2-3 mm eccentrically placed orifice was identified, and following surgical resection of the membrane the child made an uneventful recovery. This case demonstrates the need for investigating children with "asthma" who do not respond to conventional medical management. A rare but potentially correctable underlying cause may be found.
Subject(s)
Cor Triatriatum/diagnosis , Respiratory Sounds/etiology , Respiratory Tract Infections/etiology , Cardiopulmonary Bypass , Cor Triatriatum/complications , Cor Triatriatum/surgery , Disease Progression , Heart Atria/surgery , Humans , Hypertension, Pulmonary/etiology , Infant , Male , RecurrenceABSTRACT
We report the case of a woman of 34 years who had ulcerative colitis and atypical pyoderma gangrenosum. The pyoderma gangrenosum responded to conservative treatment.
Subject(s)
Facial Dermatoses/diagnosis , Neck/pathology , Pyoderma Gangrenosum/diagnosis , Adult , Anti-Inflammatory Agents/therapeutic use , Colitis, Ulcerative/complications , Cyclosporine/therapeutic use , Diagnosis, Differential , Facial Dermatoses/drug therapy , Female , Follow-Up Studies , Humans , Immunosuppressive Agents/therapeutic use , Prednisolone/therapeutic use , Pyoderma Gangrenosum/drug therapyABSTRACT
Ischaemia-reperfusion injury (IRI) is a complex interplay between biochemical, cellular, and vascular endothelial factors. The clinical sequelae are organ specific, and may also involve systemic inflammatory responses. In this article, we outline an overview of the pathophysiology of IRI, with direct reference to histological and physiological changes seen in individual organs, and present the data on experimental methods of prevention.
