ABSTRACT
Experience of surgical treatment of 171 patients, suffering hepatocellular carcinoma (HCC), was summarized. Extensive hepatic operations were performed in 99 (71.2%) patients, of them in 22.2%--on the concurrent hepatic cirrhosis background. Late results of treatment, depending on the main prognostic factors present, were analyzed. Cumulative survival in the terms of 5, 10 and 20 years have constituted 53.5, 37.3 and 28.8% accordingly. Accomplishment of a radical hepatic resection for HCC permits to achieve a durable remission of a tumoral process. While revealing a concurrent hepatic cirrhosis stage B (according to Child--Pugh classification) it is appropriate to use a hepatic transplantation and other methods of treatment, including chemoembolization, radiofrequency ablation, chemotherapy.
Subject(s)
Carcinoma, Hepatocellular/surgery , Hepatectomy/methods , Liver Neoplasms/surgery , Adolescent , Adult , Aged , Carcinoma, Hepatocellular/complications , Carcinoma, Hepatocellular/mortality , Carcinoma, Hepatocellular/pathology , Disease-Free Survival , Female , Hepatectomy/mortality , Humans , Liver Cirrhosis/complications , Liver Cirrhosis/mortality , Liver Cirrhosis/pathology , Liver Cirrhosis/surgery , Liver Neoplasms/complications , Liver Neoplasms/mortality , Liver Neoplasms/pathology , Male , Middle Aged , Neoplasm Staging , Young AdultABSTRACT
The experience of 329 gastropancreatoduodenal resections for malignant tumors of the periampullary zone has been reviewed. The obstructive jaundice complicated the disease in 237 (70%) patients. The fact required various modalities of the preoperative artificial bile drainage. To evaluate the jaundice influence on the perioperative period, patients were divided in 4 groups, considering the bile drainage modality and bilirubin blood levels. The early postoperative period was respectively analyzed, which led to the conclusion that bilirubin blood level has no influence on either intraoperative characteristics or postoperative morbidity and mortality. For the reason of that, radical treatment of the periampullary cancer, complicated by the obstructive jaundice, does not require preoperative bile drainage.
Subject(s)
Common Bile Duct/pathology , Digestive System Neoplasms , Dissection , Duodenum/pathology , Jaundice, Obstructive/surgery , Pancreas/pathology , Bilirubin/blood , Digestive System Neoplasms/complications , Digestive System Neoplasms/metabolism , Digestive System Neoplasms/physiopathology , Digestive System Neoplasms/surgery , Dissection/adverse effects , Dissection/standards , Drainage , Gastrectomy/methods , Humans , Jaundice, Obstructive/blood , Jaundice, Obstructive/etiology , Jaundice, Obstructive/physiopathology , Liver Function Tests , Pancreaticoduodenectomy/methods , Patient Selection , Postoperative Complications/metabolism , Postoperative Complications/mortality , Postoperative Complications/physiopathology , Postoperative Complications/therapy , Treatment OutcomeABSTRACT
527 patients were operated on for liver colorectal cancer metastases. Of all cases of lymphadenectomy during liver resections, lymph nodes invasion was morphologically proved in 43 patients. 3- and 5-year survival rate in this group was 12,8+/-6.6% and 6.4+/-5.6%, respectively. No patients survived a ten-year interval. Maximal follow-up period was 62 months, median - 17 months. 3-year disease-free survival rate was 5.1+/-4.8%. No 5-year disease-free survival was registered. Inclusion of oxaliplatin in adjuvant chemotherapy regimen allowed the dramatical improvement of survival rates.
Subject(s)
Antineoplastic Agents/therapeutic use , Colorectal Neoplasms/pathology , Liver Neoplasms/secondary , Liver Neoplasms/therapy , Organoplatinum Compounds/therapeutic use , Chemotherapy, Adjuvant , Combined Modality Therapy , Humans , Liver Neoplasms/drug therapy , Liver Neoplasms/surgery , Lymph Node Excision , Lymph Nodes/pathology , Lymph Nodes/surgery , Lymphatic Metastasis , Neoplasm Invasiveness , OxaliplatinABSTRACT
The authors provide a rationale for mathematically processing medical images for the progression of a medical diagnostic process. The tools made by the real-time conveyor 2D processing and visualization technology are proposed for work with medical images. The results of conveyor 2D processing of medical images as graphical presentations are given.
