Primary lung low-grade fibromyxoid sarcoma: A rare case with A diagnostic dilemma.

Low-grade fibromyxoid sarcoma (LGFMS) is a rare, low-grade malignant soft tissue tumor that is often mistaken for benign or more rarely malignant tumor types. Commonly, this tumor affects young adults and typically arises in the deep proximal extremities or trunk with frequent recurrences and can metastasize to the lungs many years late. Visceral LGFMS is extremely rare. Only a few cases of primary LGFMS of the lung have been reported. Here, we present the clinical, gross, microscopic, and immunohistochemical characteristics of Evans tumor occurring in the lung with a review of the literature and discuss the differential diagnosis in this exceptional localization.

6-minute walk distance in healthy North Africans older than 40 years: influence of parity.

The need for a 6-min walk distance (6-MWD) reference equation for healthy North African adults older than 40 years was assessed in a prospective cross-sectional study. Anthropometric data and 6-MWD were measured in 229 healthy Tunisian adults (125 women) over 40 years old. Two subgroups of 38 women were identified according to the parity (lowor=6). The published reference equations did not reliably predict measured 6-MWD. The 6-MWD was significantly correlated with gender, age, weight and height (p<0.001). The combination of these parameters explained 77% of the 6-MWD variability in the equation: 6-MWD (m)=-160.27 x gender (0: men; 1: women) - 5.14 x age (yr) - 2.23 x weight (kg)+2.72 x height (cm)+720.50. Parity accelerated the 6-MWD decline (r=-0.39, p<0.05) and women distinguished only by parity (or=6) showed different 6-MWD (589+/-60 m vs. 555+/-57 m, p<0.05). In an additional group of 30 adults prospectively studied to validate the equation, the agreement between the measured and equation-predicted 6-MWD was satisfactory. In conclusion, this reliable 6-MWD reference equation enriches the World Bank and provides an important element of interpretation for women with high parity.