ABSTRACT
Pityriasis lichenoides chronica (PLC) is an infrequent dermatosis of unknown aetiology, wholse evolution and response to treatment differs between children and adults. When PLC is recalcitrant or unresponsive to topical treatment, phototherapy is one of the main treatments used. We carried out a prospective study of adult diffuse PLC treated with narrowband ultraviolet B (NB-UVB). We treated eight patients whose disease showed no response to topical therapy, and obtained a complete response rate of 88% in a mean of 23 sessions (cumulative dose 16.99 J/cm2 ). However, the relapse rate was 43% in the first 6 months. Our results are similar to those of other published studies but there is much variability between them in the doses applied and the number of sessions needed. Further studies are necessary to devise a protocol for NB-UVB treatment of PLC.
Subject(s)
Pityriasis Lichenoides/radiotherapy , Ultraviolet Therapy/methods , Adolescent , Adult , Aged , Chronic Disease , Female , Humans , Male , Middle Aged , Prospective Studies , Radiation Dosage , Recurrence , Review Literature as Topic , Young AdultABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Middle Aged , Lichen Nitidus/diagnosis , Lichen Nitidus/radiotherapy , Phototherapy/trends , PUVA Therapy/methods , Anti-Allergic Agents/therapeutic use , Lichen Nitidus/complications , Lichen Nitidus/physiopathology , Immunotherapy/trends , Dinitrochlorobenzene/therapeutic useSubject(s)
Humans , Male , Middle Aged , Drug Eruptions/diagnosis , Ibuprofen/adverse effects , /diagnosisSubject(s)
Amoxicillin/adverse effects , Anti-Bacterial Agents/adverse effects , Exanthema/chemically induced , Infectious Mononucleosis/diagnosis , Tonsillitis/drug therapy , Exanthema/complications , Female , Humans , Infectious Mononucleosis/complications , Pain/etiology , Tonsillitis/complications , Young AdultABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Infectious Mononucleosis/diagnosis , /diagnosis , Amoxicillin/adverse effects , Drug Eruptions/diagnosis , Tonsillitis/drug therapySubject(s)
Larva Migrans/diagnosis , Adult , Exanthema/etiology , Female , Humans , Larva Migrans/complications , Pruritus/etiologyABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Exanthema/etiology , Pruritus/etiology , Larva Migrans/diagnosis , Ancylostoma/isolation & purificationABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Psoriasis/diagnosis , Fever/etiology , Dermatitis/etiologyABSTRACT
El síndrome CINCA (Chronic Infantile Neurologic Cutaneous Articular Syndrome) es una grave enfermedad inflamatoria sistémica crónica, de instauración temprana, que se caracteriza por afectación cutánea, articular y del sistema nervioso central (SNC). La clínica cutánea en forma de exantema urticariforme no pruriginoso es la primera en aparecer, siendo más o menos permanente con exacerbaciones que coinciden con brotes de fiebre, artritis y adenopatías. La biopsia de las lesiones cutáneas es muy variable, aunque destaca un infiltrado neutrofílico perivascular. El descubrimiento de mutaciones en el gen CIAS1, que codifica una proteína llamada criopirina, ha permitido añadir esta entidad al espectro de las enfermedades autoinflamatorias asociadas a criopirinas, junto con la urticaria familiar por frío y el síndrome de Muckle-Wells, implicando además nuevas opciones terapéuticas. Presentamos el caso de un varón diagnosticado de síndrome CINCA que presentó un brote de lesiones cutáneas dolorosas y fiebre, interpretándose éstas como una exacerbación de sus lesiones habituales durante un episodio febril (AU)
Chronic infantile neurologic cutaneous articular (CINCA) syndrome is a serious chronic systemic inflammatory disease that presents at a young age and that is characterized by skin, joint, and central nervous system disease. Skin symptoms are the first to appear, in the form of a longstanding non pruritic urticarial rash, with exacerbations coinciding with episodes of fever, arthritis, and enlarged lymph nodes. The findings of biopsy of skin lesions are extremely variable but characterized by perivascular neutrophilic infiltrate. With the discovery of mutations in the CIAS1 gene, which encodes a protein known as cryopyrin, this entity has been classified as one of the cryopyrin-associated autoinflammatory diseases, along with familial cold urticaria and Muckle-Wells syndrome. This discovery has also made available new therapeutic options. We present the case of a boy diagnosed with CINCA syndrome who presented with an outbreak of painful skin lesions and fever. These lesions were thought to be an exacerbation of underlying lesions during an episode of fever (AU)
Subject(s)
Humans , Male , Adult , Arthritis/diagnosis , Chronic Disease , Erythema/diagnosis , Fever/diagnosis , Nervous System Diseases/complications , Nervous System Diseases/diagnosis , Syndrome , Dermatitis/diagnosis , Exanthema/complications , Adrenal Cortex Hormones/therapeutic use , Nervous System Diseases/pathology , Nervous System Diseases/therapy , Exanthema/diagnosis , Urticaria/diagnosis , Anti-Inflammatory Agents, Non-Steroidal/therapeutic useABSTRACT
Chronic infantile neurologic cutaneous articular (CINCA) syndrome is a serious chronic systemic inflammatory disease that presents at a young age and that is characterized by skin, joint, and central nervous system disease. Skin symptoms are the first to appear, in the form of a longstanding nonpruritic urticarial rash, with exacerbations coinciding with episodes of fever, arthritis, and enlarged lymph nodes. The findings of biopsy of skin lesions are extremely variable but characterized by perivascular neutrophilic infiltrate. With the discovery of mutations in the CIAS1 gene, which encodes a protein known as cryopyrin, this entity has been classified as one of the cryopyrin-associated autoinflammatory diseases, along with familial cold urticaria and Muckle-Wells syndrome. This discovery has also made available new therapeutic options. We present the case of a boy diagnosed with CINCA syndrome who presented with an outbreak of painful skin lesions and fever. These lesions were thought to be an exacerbation of underlying lesions during an episode of fever.
Subject(s)
Arthritis/genetics , Carrier Proteins/genetics , Fever/etiology , Neurocutaneous Syndromes/diagnosis , Adrenal Cortex Hormones/therapeutic use , Adult , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Carrier Proteins/physiology , Chronic Disease , Diagnosis, Differential , Drug Therapy, Combination , Humans , Interleukin 1 Receptor Antagonist Protein/therapeutic use , Male , Meningitis, Aseptic/etiology , NLR Family, Pyrin Domain-Containing 3 Protein , Neurocutaneous Syndromes/complications , Neurocutaneous Syndromes/drug therapy , Neurocutaneous Syndromes/genetics , Neurocutaneous Syndromes/pathology , Recurrence , Sweet Syndrome/diagnosis , SyndromeABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Ecthyma/diagnosis , Streptococcal Infections/diagnosis , Streptococcus pyogenes/isolation & purification , Streptococcus pyogenes/pathogenicity , Anti-Bacterial Agents/therapeutic useABSTRACT
No disponible
Subject(s)
Humans , Female , Adolescent , Lupus Erythematosus, Systemic/diagnosis , Edema/etiology , Purpura/etiology , Pruritus/etiologyABSTRACT
No disponible
Subject(s)
Male , Adult , Humans , Nail Diseases/diagnosis , Siphonaptera , Somalia , TravelSubject(s)
Foot Dermatoses/diagnosis , Travel , Adult , Animals , Humans , Male , Siphonaptera , ToesABSTRACT
Atypical mycobacterial infections are increasingly important in immunosuppressed patients as well as in healthy hosts. The atypical mycobacterium that most commonly affects the skin is Mycobacterium marinum. The infection should be suspected upon the presence of ulcers, nodules or chronic plaques and a history of contact with fresh or salt water. Optimal therapy is yet to be established. We report a case of Mycobacterium marinum infection in a patient receiving immunosuppressive therapy that responded favourably to treatment with doxicycline. We review the different antibiotic regimens prescribed in the past years for the treatment of Mycobacterium marinum infection.
