Age related outcome in acute subdural haematoma following traumatic head injury.

Acute subdural haematoma (ASDH) is one of the conditions most strongly associated with severe brain injury. Reports prior to 1980 describe overall mortality rates for acute subdural haematomas (SDH's) ranging from 40% to 90% with poor outcomes observed in all age groups. Recently, improved results have been reported with rapid diagnosis and surgical treatment. The elderly are predisposed to bleeding due to normal cerebral atrophy related to aging, stretching the bridging veins from the dura. Prognosis in ASDH is associated with age, time from injury to treatment, presence of pupillary abnormalities, Glasgow Coma Score (GCS) or motor score on admission, immediate coma or lucid interval, computerized tomography findings (haematoma volume, degree of midline shift, associated intradural lesion, compression of basal cisterns), post-operative intracranial pressure and type of surgery. Advancing age is known to be a determinant of outcome in head injury. We present the results of a retrospective study carried out in Beaumont Hospital, Dublin, Ireland's national neurosurgical centre. The aim of our study was to examine the impact of age on outcome in patients with ASDH following severe head injury. Only cases with acute subdural haematoma requiring surgical evacuation were recruited. Mortality was significantly higher in older patients (50% above 70 years, 25.6% between 40 and 70 years and 26% below 40 years). Overall poor outcome (defined as Glasgow outcome scores 3-5) was also higher in older patients; 74.1% above 70 years, 48% between 40 and 70 years and 30% below 40 years. Poor outcome in traumatic acute subdural haematoma is higher in elderly patients even after surgical intervention.

A test of the reliability and validity of a diabetes specific quality of life scale in a Nigerian hospital.

The purpose of this study was to test the reliability of the Well-being and Diabetes Treatment Satisfaction Questionnaires among clinic patients with type 2 diabetes as well as determine the clinical correlates of these measures. A cross-sectional survey was conducted using the Well-being Questionnaire and the Diabetes Treatment Satisfaction Questionnaire. Other demographic and clinical indices of age, sex, body mass index, disease duration and blood glucose levels were also recorded. 83 responses were analysed. Subjects were aged between 25 and 75 years, mean 55.5+/-11.1 years. 50.6% were males while 49.4% were females. Mean diabetes duration was 4.9+/-6.5 years. 67 (80.7%) were receiving oral agents and dietary modification while 16 (19.3%) were on insulin therapy. The internal consistency for responses to the well-being subscales and treatment satisfaction scale produced satisfactory alpha coefficients ranging from 0.73 to 0.88 and 0.74 respectively. Inter-item correlations were ranged between 0.19 and 0.45 for depression subscale; 0.22-0.78 for anxiety subscale; 0.33-0.58 for energy subscale; 0.33-0.79 for positive well-being subscale; and -0.22 to 0.79 for the treatment satisfaction scale. Item-total correlations ranged between 0.39 and 0.87 across the two scales: well-being (0.59-0.87) and treatment satisfaction (0.39-0.78). Mean scale scores were similar in both insulin and oral hypoglycaemic drug treated patients. Positive well-being was higher in males 13.4+/-4.1 vs. 11.5+/-4.3 in females p = 0.04. None of the well-being subscale scores, or treatment satisfaction correlated with age, disease duration, body mass index or glycaemic control. The well-being and treatment satisfaction scales are reliable instruments for the measurement of diabetes specific quality of life and treatment satisfaction in Nigerians although they were originally designed and developed among a UK population. It is hoped that our data would provide the basis for future comparisons and improving diabetes care.