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Sud Med Ekspert ; 43(4): 25-9, 2000.
Article in Russian | MEDLINE | ID: mdl-10961130

ABSTRACT

Anti-Le(a) and anti-Le(b) monoclonal antibodies were obtained and attempts at evaluating their epitope specificity have been made. A method for identification of Lewis phenotypes in salivary specimens by dot-I enzyme immunoassay has been developed. Analyses of salivary samples from 72 donors detected donors with phenotypes Le(a-b-) and Le(a+b+), which was confirmed by hemagglutination test.


Subject(s)
Antibodies, Monoclonal/isolation & purification , Lewis Blood Group Antigens/immunology , Saliva/immunology , Species Specificity , Animals , Antibodies, Monoclonal/immunology , Humans , Immunoenzyme Techniques , Mice , Mice, Inbred BALB C , Phenotype , Saliva/chemistry
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