Subject(s)
Antiparasitic Agents/therapeutic use , Information Systems , Outcome Assessment, Health Care/methods , Parkinson Disease , Pharmacoepidemiology/methods , Antiparasitic Agents/economics , Humans , Parkinson Disease/drug therapy , Parkinson Disease/economics , Parkinson Disease/epidemiology , Prevalence , Russia/epidemiologyABSTRACT
To carry out a differential diagnosis of two facial dyskinesia (FD) models--facial hemispasm (FH) and facial paraspasm (FP), a combined program of electroneuromyographic (ENMG) examination has been created, using statistical analyses, including that for objects identification based on hybrid neural network with the application of adaptive fuzzy logic method and standard statistics programs (Wilcoxon, Student statistics). In FH, a lesion of peripheral facial neuromotor apparatus with augmentation of functions of inter-neurons in segmental and upper segmental stem levels predominated. In FP, primary afferent strengthening in mimic muscles was accompanied by increased motor neurons activity and reciprocal augmentation of inter-neurons, inhibiting motor portion of V pair. Mathematical algorithm for ENMG results recognition worked out in the study provides a precise differentiation of two FD models and opens possibilities for differential diagnosis of other facial motor disorders.