Increased N250 elicited by facial familiarity: An ERP study including the face inversion effect and facial emotion processing.

The present study aims to explore how familiarity modulates the neural processing of faces under different conditions: upright or inverted, neutral or emotional. To this purpose, 32 participants (25 female; age: M = 27.7 years, SD = 9.3) performed two face/emotion identification tasks during EEG recording. In the first task, to study facial processing, three different categories of facial stimuli were presented during a target detection task: famous familiar faces, faces of loved ones, and unfamiliar faces. To explore the face inversion effect according to each level of familiarity, these facial stimuli were also presented upside down. In the second task, to study emotional face processing, an emotional identification task on personally familiar and unfamiliar faces was conducted. The behavioural results showed an improved performance in the identification of facial expressions of emotion with the increase of facial familiarity, consistent with the previous literature. Regarding electrophysiological results, we found increased amplitudes of the P100, N170, and N250 for inverted compared to upright faces, independently of their degree of familiarity. Moreover, we did not find familiarity effects at the P100 and N170 time-windows, but we found that N250 amplitude was larger for personally familiar compared to unfamiliar faces. This result supports the reasoning that the facial familiarity increases the neural activity during the N250 time-window, which may be explained by the processing of additional information prompted by the viewing of our loved ones faces, in contrast to what happens with unfamiliar individuals.

Best practices in near-infrared fluorescence imaging with indocyanine green (NIRF/ICG)-guided robotic urologic surgery: a systematic review-based expert consensus.

PURPOSE: The aim of the present study is to investigate the impact of the near-infrared (NIRF) technology with indocyanine green (ICG) in robotic urologic surgery by performing a systematic literature review and to provide evidence-based expert recommendations on best practices in this field. METHODS: All English language publications on NIRF/ICG-guided robotic urologic procedures were evaluated. We followed the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) statement to evaluate PubMed®, Scopus® and Web of Science™ databases (up to April 2019). Experts in the field provided detailed pictures and intraoperative video-clips of different NIRF/ICG-guided robotic surgeries with recommendations for each procedure. A unique QRcode was generated and linked to each underlying video-clip. This new exclusive feature makes the present the first "dynamic paper" that merges text and figure description with their own video providing readers an innovative, immersive, high-quality and user-friendly experience. RESULTS: Our electronic search identified a total of 576 papers. Of these, 36 studies included in the present systematic review reporting the use of NIRF/ICG in robotic partial nephrectomy (n = 13), robotic radical prostatectomy and lymphadenectomy (n = 7), robotic ureteral re-implantation and reconstruction (n = 5), robotic adrenalectomy (n = 4), robotic radical cystectomy (n = 3), penectomy and robotic inguinal lymphadenectomy (n = 2), robotic simple prostatectomy (n = 1), robotic kidney transplantation (n = 1) and robotic sacrocolpopexy (n = 1). CONCLUSION: NIRF/ICG technology has now emerged as a safe, feasible and useful tool that may facilitate urologic robotic surgery. It has been shown to improve the identification of key anatomical landmarks and pathological structures for oncological and non-oncological procedures. Level of evidence is predominantly low. Larger series with longer follow-up are needed, especially in assessing the quality of the nodal dissection and the feasibility of the identification of sentinel nodes and the impact of these novel technologies on long-term oncological and functional outcomes.

Comparative diagnostic performance of TACT slices and its multiple source images: an in vitro study.

OBJECTIVE: To compare the diagnostic performances provided by tuned aperture computed tomography (TACT) slices and the multiple images that they originate from in the detection of primary caries on the proximal surfaces of posterior teeth. STUDY DESIGN: Eight direct digital radiography images of each of 40 posterior teeth were acquired with a digital sensor. These source images were used to generate TACT slices of the teeth. Eight trained observers were calibrated in the use of both TACT slices and the eight source images of each tooth. They were asked to assess the presence/absence of proximal caries in the teeth using a 5-point rating scale. Observers' assessments were compared with the ground truth provided by histological examination of tooth sections. Areas under the receiver operating characteristic (ROC) curves (Az) were calculated for each combination of observer and image modality. Analysis of variance (ANOVA) was used to test the ROC values for potential statistical differences. RESULTS: Mean ROC Az values were 0.760 for TACT slices and 0.771 for its multiple source images for the detection of primary proximal caries. ANOVA showed no statistically significant differences either between modalities (P = 0.656) or between observers (P = 0.851). CONCLUSION: TACT slices and its multiple source images provide comparable diagnostic performance for proximal caries detection.

Tenossinovite nodular localizada. / Localized nodular tenosynovitis

Os autores apresentam uma serie de treze casos de tenossinovite nodular localizada, todos tratados cirurgicamente. Enfatizam a hipotese de origem traumatica do tumor baseada principalmente nas alteracoes anatomopatologicas