1.
Chem Commun (Camb)
; 49(93): 10917-9, 2013 Dec 04.
Article
in English
| MEDLINE
| ID: mdl-23958894
ABSTRACT
The corrole-based catalytic antioxidant reduced the cholesterol biosynthesis ability of macrophages, harvested from mice treated with it. and a non-redox active analogue of it affect the committed step of the biosynthetic pathway--the HMG-CoA reductase catalysed reaction--by acting as allosteric inhibitors of this key enzyme.