Phase-Resolved Partial Discharge (PRPD) Pattern Recognition Using Image Processing Template Matching.

This paper proposes a new method for recognizing, extracting, and processing Phase-Resolved Partial Discharge (PRPD) patterns from two-dimensional plots to identify specific defect types affecting electrical equipment without human intervention while retaining the principals that make PRPD analysis an effective diagnostic technique. The proposed method does not rely on training complex deep learning algorithms which demand substantial computational resources and extensive datasets that can pose significant hurdles for the application of on-line partial discharge monitoring. Instead, the developed Cosine Cluster Net (CCNet) model, which is an image processing pipeline, can extract and process patterns from any two-dimensional PRPD plot before employing the cosine similarity function to measure the likeness of the patterns to predefined templates of known defect types. The PRPD pattern recognition capabilities of the model were tested using several manually classified PRPD images available in the existing literature. The model consistently produced similarity scores that identified the same defect type as the one from the manual classification. The successful defect type reporting from the initial trials of the CCNet model together with the speed of the identification, which typically does not exceed four seconds, indicates potential for real-time applications.

Identification of HPV16's E6 gene in suspected cases of cervical lesions and docking Study of its L1 protein with active components of Echinacea purpurae.

Background: HPV 16 is the primary etiologic agent of cervical cancer and the presence of L1 and E6 oncoproteins are largely responsible for its virulence. It was the objective of this study to identify HPV16 isolates from suspected cases of cervical cancer at Specialist Hospital Sokoto and Sir Yahaya Memorail Hospiatal Birnin Kebbi, Nigeria and also to identify potent HPV16's L1 protein inhibitor using in silico analysis. Methods: A total of 144 cervical samples consisting of 21 low grade squamous intraepithelial lesion, 6 high grade lesion and 117 negative pap smears were collected. The samples were subjected for molecular detection using PCR targeting E6 gene of the virus. Data generated for the molecular prevalence was statistically analyzed using Chi-square method. AutoDock Vina was used to carry out the molecular docking between 2hr5 and Chicoric acid, curcumin and Echinacoside. Results: Out of the 144 samples, 24 samples were positive for the PCR representing 16.9% molecular prevalence rate. There is statistically significant association between cyto-diagnoses and presence of HPV16 (P < 0.05). Docking analysis showed that the Chicoric acid components of Echinacea purpurae have strong binding affinity (-8.7 kcal/mol) to the L1 protein of the HPV. Conclusion: This study provides data on HPV 16 epidemiology in northern Nigeria, and also provides novel evidence for consideration on certain interacting residues, when synthesizing Anti-HPV compounds in the wet lab.

Blood pressure and heart rate adjustment following acute Frenkel's ambulatory exercise in chronic hemiparetics stroke survivors: a comparative study.

BACKGROUND: Frenkel's ambulatory activity has been routinely employed by physiotherapists for rehabilitation of gait coordination, however, its immediate influence on blood pressure and heart rate has not been investigated. OBJECTIVE: To investigate the acute effect of Frenkel's ambulatory activity on blood pressure and heart rate of chronic hemiparetic stroke survivors. METHOD: Using a comparative study design, 60 chronic hemiparetic stroke survivors of varying onset of stroke, ≤6, >6-11 and ≥12 months were subjected to a 2-minute Frenkel's ambulatory activity on marked footsteps (from standard adult described footsteps). Participants were assessed for both blood pressure and heart rate before and after the Frenkel's ambulatory activity. RESULTS: Blood pressure and heart rate significantly increased (p<0.05) following Frenkel's ambulatory activity in all the 3 categories of stroke onset above baseline. However, there was no significant difference (p>0.05) across the onsets in both blood pressure and heart rate responses. CONCLUSION: The outcome of this study indicated that Frenkel's ambulatory activity has the propensity to increase blood pressure and heart rate of hemiparetic stroke survivors irrespective of the onset of stroke. We recommend a pre, within and post-activity monitoring of stroke survivors while subjecting them to Frenkel's ambulatory activity.