ABSTRACT
The article represents results of radionuclide study of hormonal levels and pulmonary microcirculation in anthracosilicosis. The authors discuss mechanisms underlying influence of vasoactive hormones on pulmonary microcirculation. The authors revealed relationships between hormonal and vascular disorders in anthracosilicosis.
Subject(s)
Anthrax/complications , Anthrax/metabolism , Epinephrine/metabolism , Hydrocortisone/metabolism , Insulin/metabolism , Occupational Diseases/metabolism , Pulmonary Artery/metabolism , Silicosis/complications , Silicosis/metabolism , Testosterone/metabolism , Anthrax/diagnosis , Humans , Lipid Peroxidation/physiology , Occupational Diseases/diagnosis , Silicosis/diagnosisABSTRACT
The paper deals with changes in hormonal homeostasis under the long-term influence of industrial and ecological factors. It presents data available in the literature on adaptive and abnormal hormonal changes in workers exposed to noxious agents and in the residents of ecologically poor regions. Emphasis is laid on hormonal imbalance in the pathogenesis of different diseases, including occupational ones.
Subject(s)
Air Pollution/adverse effects , Ecology , Hormones/physiology , Occupational Diseases , Adolescent , Adult , Child , Female , Homeostasis , Humans , Hydrocortisone/physiology , Male , Occupational Diseases/chemically induced , Occupational Diseases/etiology , Occupational Diseases/physiopathology , Pregnancy , Rural Population , Stress, Physiological/physiopathology , Urban Population , Vasopressins/physiology , Vibration/adverse effectsABSTRACT
The hormonal background of coal-pit miners was studied by radioimmunoassay method. It was determined, that adaptation to coal-dust influence proceeds by protective-compensatory increasing of cortisol, thyroid hormones and insulin levels. When a functional reserves of endocrine glands exhausted, the adaptation breaks down and pneumoconiosis may arise.
Subject(s)
Endocrine System Diseases/etiology , Mining , Occupational Exposure/adverse effects , Adult , Endocrine System Diseases/blood , Humans , Insulin/blood , Male , Middle Aged , Russia , Silicosis/blood , Testosterone/blood , Thyroxine/blood , Triiodothyronine/bloodSubject(s)
Breast Neoplasms/diagnosis , Glucose , Thermography/methods , Diagnosis, Differential , Female , HumansABSTRACT
The paper is concerned with the results of examination of 157 women with breast diseases. Breast cancer was diagnosed in 94 patients, benign diseases in 63. The combined use of the thermographic and radionuclide methods was shown to raise the accuracy of breast cancer diagnosis.