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2.
Psychopharmacol Bull ; 52(1): 91-94, 2022 02 25.
Article in English | MEDLINE | ID: mdl-35342204

ABSTRACT

Avoidant/Restrictive Food Intake Disorder and misophonia seem to be overrepresented in autism spectrum disorder. Literature is mute on psychopharmacotherapy in these complex presentations. Here, authors report on a challenging case of low-functioning ASD child with comorbid ARFID and misophonia that responded favorably to a low-dose risperidone. This is followed by a brief discussion of purported pharmacodynamic mechanisms and relevant literature.


Subject(s)
Autism Spectrum Disorder , Autistic Disorder , Avoidant Restrictive Food Intake Disorder , Feeding and Eating Disorders , Autism Spectrum Disorder/complications , Autism Spectrum Disorder/drug therapy , Autistic Disorder/drug therapy , Child , Humans , Risperidone
4.
J Nerv Ment Dis ; 209(9): 691-692, 2021 Sep 01.
Article in English | MEDLINE | ID: mdl-34448737

ABSTRACT

ABSTRACT: Burgeoning body of evidence from neuroscience is pouring in highlighting a potential association between gut microbiota with the pathophysiology of depression and anxiety. Manipulation of gut microbiota may be then useful to decode this role and to provide novel therapeutics for major depressive disorder (MDD), developing microbiota-related biomarkers to stratify patients at risk and to delineate more homogeneous biotypes of MDD.


Subject(s)
Depressive Disorder, Major/microbiology , Gastrointestinal Microbiome , Host Microbial Interactions , Animals , Anxiety/microbiology , Biomarkers , Depression/microbiology , Depressive Disorder, Major/diagnosis , Depressive Disorder, Major/diet therapy , Humans , Mice , Prebiotics , Probiotics/therapeutic use , Rats
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