ABSTRACT
Curvularia is a saprobic dematiaceous mold that has been associated with a wide spectrum of human infection. In non-immunosuppressed patients, infections frequently involve the paranasal sinus, skin, and soft tissue, whereas systemic dissemination and endocarditis are extremely rare. The optimal antifungal therapy for Curvularia infection is not known, and responses to treatment with amphotericin B, miconazole, ketoconazole, terbinafine, and itraconazole have been reported. We describe a patient with an invasive dematiaceous fungal sinusitis who was immunocompetent and was infected with Curvularia. The patient was successfully treated with oral itraconazole by otolaryngology and the infectious disease service.
Subject(s)
Dermatomycoses/diagnosis , Facial Dermatoses/microbiology , Mitosporic Fungi/isolation & purification , Antifungal Agents/therapeutic use , Chronic Disease , Debridement , Humans , Itraconazole/therapeutic use , Male , Maxillary Sinusitis/microbiology , Middle Aged , Palate, Hard/microbiology , Skin Ulcer/microbiologySubject(s)
Dental Care for Chronically Ill , Dental Implantation, Endosseous , Dental Implants , HIV Infections/immunology , Adult , Anti-HIV Agents/therapeutic use , Antiretroviral Therapy, Highly Active , CD4 Lymphocyte Count , HIV Infections/drug therapy , Humans , Immunosuppressive Agents/therapeutic use , Male , Middle AgedSubject(s)
Alveolar Ridge Augmentation/methods , Bone Morphogenetic Proteins/therapeutic use , Maxilla/surgery , Maxillary Sinus/surgery , Bone Morphogenetic Proteins/administration & dosage , Dental Implants , Drug Carriers , Gelatin Sponge, Absorbable , Humans , Osseointegration/drug effects , Osseointegration/physiology , Osteogenesis/drug effects , Osteogenesis/physiologyABSTRACT
The association between HIV infection and the success of osseointegrated dental implants is unknown. Recent reports in the dental literature show no difference between HIV-positive and HIV-negative patients in terms of infection rate after surgical procedures. A case report documenting the successful placement and osseointegration of eight endosseous dental implants in an HIV-positive patient is presented. This article also reviews the complications of implant procedures and the outcomes of surgical procedures in HIV-positive patients.
