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1.
Nat Prod Commun ; 12(2): 205-206, 2017 Feb.
Article in English | MEDLINE | ID: mdl-30428212

ABSTRACT

Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with a-pinene (29.7%), 8-3-carene (14.2%), and a mixture of P-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 µL/mL for S. aureus and 28.4 µL/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 µL/mL and 113.6 µL/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.


Subject(s)
Angelica archangelica/chemistry , Anti-Bacterial Agents/pharmacology , Oils, Volatile/pharmacology , Microbial Sensitivity Tests , Oils, Volatile/analysis , Plant Roots/chemistry
2.
Nat Prod Commun ; 12(2): 309-317, 2017 Feb.
Article in English | MEDLINE | ID: mdl-30428236

ABSTRACT

The liver has the crucial role in the regulation of various physiological processes and in the excretion of endogenous waste metabolites and xenobiotics. Liver structure impairment can be caused by various factors including microorganisms, autoimmune diseases, chemicals, alcohol and drugs. The plant kingdom is. full of liver protective chemicals such as phenols, coumarins, lignans, essential oils, monoterpenes, carotenoids; glycosides, flavonoids, organic acids, lipids,- alkaloids and xanthenes. Apiaceae plants are usually used as a vegetable or as a spice, but their other functional properties are also very important. This review highlights the significance of caraway, dill, cumin, aniseed, fennel, coriander, celery, lovage, angelica, parsley and carrot, which are popular vegetables and spices, but possess hepatoprotective potential. These plants can be used for medicinal applications to patients who suffer from liver damage.


Subject(s)
Apiaceae , Liver/drug effects , Protective Agents/pharmacology , Anethum graveolens , Animals , Apium , Coriandrum , Cuminum , Foeniculum , Humans , Pimpinella
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