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1.
Actas esp. psiquiatr ; 37(1): 42-48, ene.-feb. 2009. ilus, tab
Article in Spanish | IBECS | ID: ibc-112130

ABSTRACT

Introducción. Este estudio se realizó para identificar el perfil psicopatológico de los pacientes esquizofrénicos suicidas en período de estabilidad y contribuir a definir los aspectos de rasgo de estas variables. Método. Los pacientes esquizofrénicos que ingresaron consecutivamente y que cumplían criterios de «suicidas» y «no suicidas» fueron evaluados en situación basal y al año, en cuanto a variables sociodemográficas, clínicas generales y psicopatológicas, mediante las subescalas positiva y negativa de la Escala de Síndromes Negativo y Positivo (PANSS), Escala de Depresión de Calgary, Escala de Desesperanza de Beck y Escala de Insight de Amador (primeros tres ítems). Resultados. Ciencuenta y siete de 73 pacientes pudieron ser reevaluados. El grupo suicida mostró mayores puntuaciones de depresión y desesperanza. La desesperanza y la menor sintomatología negativa permitieron identificar a la mayoría de los pacientes suicidas (66,7%) y no suicidas (70%). La desesperanza fue la variable más importante para identificar el riesgo de suicidio. Conclusiones. El perfil hallado en condiciones de estabilidad clínica complementa el perfil identificado en fase aguda en la literatura y podría permitir una mejora en la identificación del riesgo suicida y orientar intervenciones preventivas (AU)


Introduction. This study aimed to of identify the psychopathological profile of suicidal schizophrenic patients during a period of stability, thereby helping to define the trait aspect of these variables. Method. Consecutively admitted schizophrenic patients fulfilling criteria for «suicidal» and «non-suicidal» groups were assessed at baseline and one year later for sociodemographic, general clinical and psychopathological features, by the positive and negative subscales of the Positive and Negative Syndromes Scale (PANSS), Calgary Depression Scale, Beck Hopelessness Scale and Amador Insight Scale (first three items). Results. A total of 57 of 73 patients were available for re-evaluation. The suicidal group showed higher depression and hopelessness scores. Hopelessness and lower negative symptomatology identified most of the suicidal (66.7%) and non-suicidal (70%) patients. Hopelessness was the most important variable for identifying suicidality. Conclusions. Under conditions of illness stability, this profile complements the acute phase profiles identified by most studies in the literature, and should foster improved risk recognition for targeting preventive interventions (AU)


Subject(s)
Humans , Schizophrenia/complications , Schizophrenia/diagnosis , Suicide/statistics & numerical data , Suicide/trends , Schizotypal Personality Disorder
2.
Actas Esp Psiquiatr ; 34(5): 352-4, 2006.
Article in Spanish | MEDLINE | ID: mdl-16991025

ABSTRACT

INTRODUCTION: Although association between beta blockers and depression has been reported since decades ago, the subject is still controversial. Most evidence supporting an association has been based on case reports or case series. Epidemiologic studies and randomized clinical trials have not generally supported this association. If this association exists, possible causes of disparity of findings may include methodological difficulties, and/or weak association. CASE SUMMARY: We present a case of a 67 year old woman, without personal history of psychiatric illness or stress factors, who develops a depressive episode after initiating treatment with atenolol. The symptoms remitted rapidly when atenolol was discontinued, and an antidepressant was prescribed during a short period. CONCLUSIONS: This case report suggests the existence of an association between a beta blocker, atenolol, and depression.


Subject(s)
Adrenergic beta-Antagonists/adverse effects , Atenolol/adverse effects , Depression/chemically induced , Aged , Female , Humans
3.
Actas esp. psiquiatr ; 34(5): 352-354, sept.-oct. 2006. ilus
Article in Es | IBECS | ID: ibc-051819

ABSTRACT

Introducción. Aunque desde hace décadas se ha señalado la asociación entre betabloqueantes y depresión, este tema permanece en controversia. La asociación ha sido señalada fundamentalmente en estudios de casos únicos o series de casos, mientras que los estudios epidemiológicos y ensayos clínicos aleatorizados han ofrecido escaso sustento a esta hipótesis. De existir tal asociación, las posibles causas de la disparidad de hallazgos serían las dificultades metodológicas, y/o que se trate de una asociación débil.Caso clínico. Se presenta un caso clínico de una paciente de 67 años, sin antecedentes psiquiátricos ni factores estresantes, que desarrolla un episodio depresivo tras iniciar tratamiento con atenolol, el cual remite rápidamente tras la supresión del mismo y de iniciar tratamiento antidepresivo durante un corto período de tiempo.Conclusiones. Este caso sugiere la existencia de asociación entre un betabloqueante, el atenolol, y la depresión


Introduction. Although association between beta blockers and depression has been reported since decades ago, the subject is still controversial. Most evidence supporting an association has been based on case reports or case series. Epidemiologic studies and randomized clinical trials have not generally supported this association. If this association exists, possible causes of disparity of findings may include methodological difficulties, and/or weak association.Clinical case. We present a case of a 67 year old woman, without personal history of psychiatric illness or stress factors, who develops a depressive episode after initiating treatment with atenolol. The symptoms remitted rapidly when atenolol was discontinued, and an antidepressant was prescribed during a short period.Conclusions. This case report suggests the existence of an association between a beta blocker, atenolol, and depression


Subject(s)
Female , Aged , Humans , Adrenergic beta-Agonists/adverse effects , Atenolol/adverse effects , Depression/chemically induced , Antidepressive Agents/therapeutic use
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