ABSTRACT
An artificial circulation apparatus consisting of two membrane pneumatic adaptive diaphragmatic-type pumps and artificial film-type lungs and principle of its operation are described. The apparatus permits maintaining volume blood flow to 800 ml/min during organism resuscitation after endured clinical death including prolonged one as well.
Subject(s)
Extracorporeal Membrane Oxygenation/instrumentation , Heart Arrest, Induced , Myocardial Reperfusion/instrumentation , Animals , Animals, Laboratory , Dogs , Equipment Design , USSRSubject(s)
Hemoperfusion , Pancreatitis/therapy , Peritonitis/therapy , Resuscitation , Adult , Aged , Animals , Dogs , Humans , Middle AgedSubject(s)
Blood Coagulation , Hemoperfusion , Animals , Blood Coagulation Tests , Dogs , Platelet AggregationSubject(s)
Cardiovascular Diseases/etiology , Hemodynamics , Hemoperfusion/adverse effects , Animals , DogsABSTRACT
Conditioned activity and vegetative reactions were studied in dogs which repeatedly underwent clinical death from electrical trauma and were reanimated by donor artificial blood circulation. (The first clinical death was provoked 15 to 18 months prior to the repeated death and was caused by drowning and blood loss). On the first few days after reanimation the functions of the higher parts of the CNS and the vegetative nervous system were considerably disturbed. This was manifested in diminished effector reactions to conditioned stimuli, in narcotic and ultraparadoxal phases in conditioned activity, in tachycardia and a higher respiratory rate. The disturbances gradually diminished and by the 5th to 13th day following reanimation completely disappeared. The nature and depth of the disturbances correlated with the basic properties of the animals' type of higher nervous activity. The conditioned reactions were restored despite the retained pronounced dystrophic and destructive changes in the cerebral cortex. This is significant proof of important compensatory capacity for conditioned activity in dogs.