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1.
Teach Learn Med ; : 1-12, 2023 Aug 17.
Article in English | MEDLINE | ID: mdl-37592855

ABSTRACT

PHENOMENON: Students become physicians not only by mastering medical knowledge, but also through a process of Professional Identity Formation (PIF). In this study, we used the conceptual framework of Jarvis-Selinger et al. to explore the impact of COVID, as a major public health crisis, on the PIF of preclinical medical students in our country. APPROACH: At two U.S. medical schools, we interviewed 28 medical students twice as they moved from first to second year during the 2020-2021 COVID pandemic and explored the impact of COVID-19 on PIF. We coded the transcribed interviews and identified themes using constructivist thematic analysis. FINDINGS: We identified three themes: 1) mental health and wellness impacts; 2) inhabiting identity as a health professional during COVID; and 3) questioning the role of physicians in society. Routines and support systems were disrupted, undermining wellness and confidence in professional choices. Students noted the need to be public health role models, and COVID prompted feelings of pride, while also causing them to question expectations of self-sacrifice amid a new politicization of medicine. Students felt that physicians must be increasingly engaged in public health and political communication. INSIGHTS: Our findings inform medical educators seeking to build a scaffolding to support PIF during a public health crisis, and highlight the importance of current events and politics on PIF. Our recommendations include the need for student support, longitudinal mentorship, curricular space to discuss the impact of sociopolitical factors on PIF, and revisiting foundational concepts such as professionalism to take into account the social and political context. Our findings add to understanding of PIF during the COVID pandemic, but are also relevant to teaching and learning during future public health crises.

2.
Cortex ; 158: 4-23, 2023 01.
Article in English | MEDLINE | ID: mdl-36403380

ABSTRACT

The case of JP, reported by Ackerly and Benton in 1948 with a detailed follow-up by Ackerly in 1964, stands as the index case of developmental prefrontal damage and its impact on social adaptation. Although the 1948 case report included findings from a 1933 pneumoencephalogram and exploratory craniotomy, a definitive cause was never established for JP's prefrontal damage. Etiologies were never determined for the left-sided seizures that occurred when JP was age four, nor for the progressive anterograde amnesia that JP developed in middle age. Given Ackerly's thoroughness and long-term follow-up of his patient, it was hoped that a brain cutting would have been done, though no report of a post-mortem examination was published. The lead author of this paper (SB) set out to discover what had happened to JP after Ackerly's 1964 report and whether a brain cutting had in fact occurred. Using a variety of investigative approaches, it was discovered that a post-mortem brain examination had taken place. Those present at the brain cutting were identified, and the still-living witnesses to the brain cutting were interviewed. Previously unpublished, relevant materials were uncovered from archival sources. A film of the brain cutting, as well as photos, were located. A film of Ackerly interviewing JP prior to JP's death at age sixty-four also was found. The authors studied autopsy findings in the newly discovered video and still images. These findings were judged consistent with massive perinatal hemorrhagic damage to both frontal lobes. JP's left-sided seizures were likely due to activation of a focus from his congenital brain damage. The anterograde amnesia that was documented when JP was twenty-five and that was noted to worsen when he was forty-nine remains unexplained but may have been related to slowly progressive hydrocephalus. This paper expands what is known about the case of JP, making it the only report of a person with congenital frontal injury followed for their entire life including post-mortem brain examination.


Subject(s)
Amnesia, Anterograde , Brain Injuries , Male , Middle Aged , Humans , Brain , Frontal Lobe , Seizures
3.
PRiMER ; 5: 29, 2021.
Article in English | MEDLINE | ID: mdl-34532649

ABSTRACT

INTRODUCTION: With growing efforts to provide comprehensive and inclusive sexual health care, family medicine clerkships are well positioned to educate learners about a spectrum of related topics. This study investigated the current state of sexual health instruction in family medicine clerkships, including specific factors impacting its delivery. METHODS: Questions about sexual health curricula were created and included as part of the 2020 Council of Academic Family Medicine's Educational Research Alliance survey of family medicine clerkship directors. The survey was distributed via email to 163 recipients between June 1, 2020 and June 25, 2020. RESULTS: One hundred five (64.42%) of 163 clerkship directors responded to the survey. Our results revealed that during family medicine clerkships, family planning, contraception, and pregnancy options counseling are covered significantly more often than topics related to sexual dysfunction and satisfaction and LGBTQ+ health. Most clerkship directors (91.5%) reported less than 5 hours of sexual health training in their curriculum. Those with more dedicated sexual health curricular hours were more likely to include simulation. Lack of time (41.7%) was the most frequently reported barrier to incorporating sexual health content into the clerkship. CONCLUSIONS: Coverage of sexual health topics during the family medicine clerkship is limited in scope and delivery. To support curricular development and integration, future studies should more thoroughly examine the factors influencing the inclusion of sexual health content in family medicine clerkships as well as the development of assessment methods to determine competency.

4.
Neonatal Netw ; 39(6): 363-368, 2020 Nov 01.
Article in English | MEDLINE | ID: mdl-33318233

ABSTRACT

In the United States, pregnant women are screened for hepatitis B antigen because of the significant risk of perinatal vertical transmission of hepatitis to the fetus. It is important that the maternal hepatitis B antigen screen is documented in the medical record to ensure appropriate prophylaxis for the neonate. The purpose of this column is to discuss the pathophysiology of hepatitis B, as well as the screening process and prophylaxis for the neonate.


Subject(s)
Hepatitis B , Pregnancy Complications, Infectious , Female , Hepatitis B/diagnosis , Hepatitis B/prevention & control , Hepatitis B Surface Antigens , Humans , Infant, Newborn , Infectious Disease Transmission, Vertical/prevention & control , Pregnancy , Pregnancy Complications, Infectious/diagnosis
5.
R Soc Open Sci ; 3(4): 160076, 2016 Apr.
Article in English | MEDLINE | ID: mdl-27152222

ABSTRACT

Animals communicating via scent often deposit composite signals that incorporate odorants from multiple sources; however, the function of mixing chemical signals remains understudied. We tested both a 'multiple-messages' and a 'fixative' hypothesis of composite olfactory signalling, which, respectively, posit that mixing scents functions to increase information content or prolong signal longevity. Our subjects-adult, male ring-tailed lemurs (Lemur catta)-have a complex scent-marking repertoire, involving volatile antebrachial (A) secretions, deposited pure or after being mixed with a squalene-rich paste exuded from brachial (B) glands. Using behavioural bioassays, we examined recipient responses to odorants collected from conspecific strangers. We concurrently presented pure A, pure B and mixed A + B secretions, in fresh or decayed conditions. Lemurs preferentially responded to mixed over pure secretions, their interest increasing and shifting over time, from sniffing and countermarking fresh mixtures, to licking and countermarking decayed mixtures. Substituting synthetic squalene (S)-a well-known fixative-for B secretions did not replicate prior results: B secretions, which contain additional chemicals that probably encode salient information, were preferred over pure S. Whereas support for the 'multiple-messages' hypothesis underscores the unique contribution from each of an animal's various secretions, support for the 'fixative' hypothesis highlights the synergistic benefits of composite signals.

6.
Int J Law Psychiatry ; 41: 89-94, 2015.
Article in English | MEDLINE | ID: mdl-25857854

ABSTRACT

The current study explores associations between implicit and explicit aggression in young adult male prisoners, seeking to apply the Reflection-Impulsive Model and indicate parity with elements of the General Aggression Model and social cognition. Implicit cognitive aggressive processing is not an area that has been examined among prisoners. Two hundred and sixty two prisoners completed an implicit cognitive aggression measure (Puzzle Test) and explicit aggression measures, covering current behaviour (DIPC-R) and aggression disposition (AQ). It was predicted that dispositional aggression would be predicted by implicit cognitive aggression, and that implicit cognitive aggression would predict current engagement in aggressive behaviour. It was also predicted that more impulsive implicit cognitive processing would associate with aggressive behaviour whereas cognitively effortful implicit cognitive processing would not. Implicit aggressive cognitive processing was associated with increased dispositional aggression but not current reports of aggressive behaviour. Impulsive implicit cognitive processing of an aggressive nature predicted increased dispositional aggression whereas more cognitively effortful implicit cognitive aggression did not. The article concludes by outlining the importance of accounting for implicit cognitive processing among prisoners and the need to separate such processing into facets (i.e. impulsive vs. cognitively effortful). Implications for future research and practice in this novel area of study are indicated.


Subject(s)
Aggression/psychology , Prisoners/psychology , Cognition , Humans , Male , Personality , Social Behavior , Surveys and Questionnaires , Young Adult
8.
J Fam Plann Reprod Health Care ; 39(2): 97-101, 2013 Apr.
Article in English | MEDLINE | ID: mdl-22923279

ABSTRACT

INTRODUCTION: In the UK half of all pregnancies are unplanned and half of teenage pregnancies terminated. Southwark and Lambeth have the highest teenage conception rates in London. In 2009, many teenage pregnancies in Southwark led to terminations. A contraception service was established where qualified pharmacists supplied oral contraception (OC) using a patient group direction (PGD). This service evaluation aimed to assess this service delivered in five community pharmacies. METHODS: Monthly data were submitted by each pharmacy to the Primary Care Trust on consultations, pills supplied, initial or subsequent supply and client referral. For specified periods consultation time was collected and a clinical notes audit undertaken. Client satisfaction was determined using a structured questionnaire returned to the pharmacy. Mystery shoppers were employed to assess the service. RESULTS: A total of 741 consultations were undertaken by seven pharmacists at five community pharmacies (October 2009-June 2011) with many (45.5%) occurring following emergency contraception supply. The mean consultation time was 19 minutes . Combined OC was most commonly supplied with nearly half (46.1%) of initial supplies to first-time pill users. Most consultations (92.2%) were with women aged under 30 years, with 22.5% aged under 20. Most consultations were with black or black British clients. Of the 99 women who completed the satisfaction questionnaires, most clients were very satisfied or satisfied with the service and felt comfortable talking to the pharmacist about contraception. CONCLUSIONS: Trained pharmacists were clinically competent and provided OC in community pharmacy according to a PGD. This service was accessed by the target population; young women using emergency hormonal contraception who had not previously used OC. Clients were largely very satisfied with the service.


Subject(s)
Contraceptives, Oral/therapeutic use , Pharmacies , Adolescent , Adult , Age Factors , Contraception, Postcoital/methods , Contraceptives, Oral/supply & distribution , Female , Humans , Patient Satisfaction , Pharmacies/standards , Pharmacies/statistics & numerical data , Program Evaluation , Referral and Consultation/statistics & numerical data , Surveys and Questionnaires , Young Adult
9.
Am J Psychother ; 66(4): 313-30, 2012.
Article in English | MEDLINE | ID: mdl-23393991

ABSTRACT

When children are abused they utilize strategies already in place to cope with stress. These strategies develop during early life within the family and may be part of the unconscious framework formed within attachments and relationships. The case presented illustrates a teen-aged girl who was the victim of sexual abuse and experienced depression, PTSD and substance abuse. This paper describes the psychodynamic psychotherapy used to examine the patient's coping skills, which predated the abuse, and how these coping mechanisms were used to ameliorate her symptoms.


Subject(s)
Child Abuse, Sexual/psychology , Child Abuse, Sexual/therapy , Object Attachment , Psychoanalytic Therapy/methods , Adaptation, Psychological , Adolescent , Alcoholism/psychology , Alcoholism/therapy , Combined Modality Therapy , Comorbidity , Depressive Disorder/psychology , Depressive Disorder/therapy , Family Conflict/psychology , Family Therapy/methods , Female , Humans , Individuation , Social Adjustment , Stress Disorders, Post-Traumatic/psychology , Stress Disorders, Post-Traumatic/therapy , Suicidal Ideation
11.
J Vet Emerg Crit Care (San Antonio) ; 20(4): 436-40, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20731810

ABSTRACT

OBJECTIVE: To characterize the clinical features and population differences among cats sustaining traumatic and nontraumatic rib fractures. DESIGN: Retrospective clinical study. SETTING: University small animal hospital. ANIMALS: Thirty-three cats with radiographic evidence of rib fractures. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Cats with rib fractures were identified by performing a computer search of the radiology database. Thirty-three cats that sustained rib fractures were identified between January 2000 and September 2009. Seventeen cats had fractures due to trauma and 16 were deemed to occur from nontraumatic causes. A Mann-Whitney rank-sum test revealed statistically significant differences in the median ages between the 2 groups. Older cats were more likely to sustain rib fractures as a result of a presumed nontraumatic causes. A Chi-square analysis showed that nontraumatic fractures occurred significantly more often in the midbody region and involved the 9th-13th ribs. The majority of cats with presumed nontraumatic rib fracture had respiratory disease; the remaining cats had chronic renal disease or neoplasia. Cats with traumatic rib fractures had external signs of trauma. CONCLUSION: Rib fractures in cats may be clearly associated with trauma, or may be an incidental finding in cats with comorbidities. Cats with diseases that cause prolonged respiratory effort or coughing, metabolic diseases, or certain neoplasms, are at increased risk of spontaneous nontraumatic rib fractures.


Subject(s)
Cat Diseases/epidemiology , Cat Diseases/etiology , Cats/injuries , Rib Fractures/veterinary , Animals , Cat Diseases/diagnostic imaging , Comorbidity , Databases, Factual , Female , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/epidemiology , Kidney Failure, Chronic/veterinary , Male , Massachusetts/epidemiology , Neoplasms/complications , Neoplasms/epidemiology , Neoplasms/veterinary , Radiography , Respiratory Tract Diseases/complications , Respiratory Tract Diseases/epidemiology , Respiratory Tract Diseases/veterinary , Retrospective Studies , Rib Fractures/diagnostic imaging , Rib Fractures/epidemiology , Rib Fractures/etiology , Schools, Veterinary , Wounds and Injuries/complications , Wounds and Injuries/epidemiology , Wounds and Injuries/veterinary
12.
Biol Cell ; 102(1): 51-62, 2009 Oct 12.
Article in English | MEDLINE | ID: mdl-19702578

ABSTRACT

BACKGROUND INFORMATION: Rab11 and Rab14 are two related Rab GTPases that are believed to function in endosomal recycling and Golgi/endosome transport processes. We, and others, have identified a group of proteins that interact with Rab11 and function as Rab11 effectors, known as the Rab11-FIPs (family interacting proteins). This protein family has been sub-classified into two groups - class I FIPs [FIP2, RCP (Rab coupling protein) and Rip11 (Rab11-interacting protein)] and class II FIPs (FIP3 and FIP4). RESULTS: In the present study we identify the class I FIPs as dual Rab-binding proteins by demonstrating that they also interact with Rab14 in a GTP-dependent manner. We show that these interactions are specific for the class I FIPs and that they occur via their C-terminal regions, which encompass the previously described RBD (Rab11-binding domain). Furthermore, we show that Rab14 significantly co-localizes with the TfnR (transferrin receptor) and that Rab14 Q70L co-localizes with Rab11a and with the class I FIPs on the ERC (endosomal recycling compartment) during interphase. Additionally, we show that during cytokinesis Rab14 localizes to the cleavage furrow/midbody. CONCLUSIONS: The data presented in the present study, which identifies the class I FIPs as the first putative effector proteins for the Rab14 GTPase, indicates greater complexity in the Rab-binding specificity of the class I FIP proteins.


Subject(s)
rab GTP-Binding Proteins/metabolism , Binding Sites , Cell Cycle/physiology , Cell Line, Tumor , Endosomes/metabolism , Female , Fluorescent Antibody Technique , Guanosine Triphosphate/metabolism , Humans , Protein Binding , Protein Transport/physiology
13.
Law Hum Behav ; 30(1): 11-30, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16729206

ABSTRACT

In a simulated products liability trial, we tested the effects of bifurcating decisions regarding compensatory and punitive damage awards. Fifty-nine groups of 5-7 jurors heard evidence in a unitary or bifurcated format, deliberated about the case to a unanimous decision, and awarded damages. Trial bifurcation decreased variability in compensatory damage awards across juries hearing the same case, and also decreased the tendency for juries to award extremely high compensatory damages. In addition, deliberation led to lower compensatory awards in the low injury severity condition and higher awards in the high injury severity condition. Jurors reported that they were using evidence more appropriately when the decisions were bifurcated. Implications of evidence bifurcation in civil trials are discussed.


Subject(s)
Compensation and Redress/legislation & jurisprudence , Decision Making , Liability, Legal/economics , Adolescent , Adult , Female , Humans , Judgment , Male , Multivariate Analysis , Punishment , United States
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